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Euphorbia factor L1, a toxic diterpene ester found in the Euphorbia plant genus, is known for its skin irritation and blistering effects upon contact. It possesses potent irritant properties towards the skin and mucous membranes, making it a notable chemical within the plant. Despite its toxicity, Euphorbia factor L1 has been recognized for its potential as a source of natural rubber and has garnered interest for its cytotoxic effects in cancer therapy. However, its hazardous nature necessitates careful handling and management to prevent exposure and adverse effects on humans and animals.

76376-43-7

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76376-43-7 Usage

Uses

Used in Natural Rubber Production:
Euphorbia factor L1 is used as a source of natural rubber for its potential in contributing to the production of this essential material, which has various industrial applications.
Used in Cancer Therapy Research:
Euphorbia factor L1 is used as a subject of research in cancer therapy due to its cytotoxic effects, which may offer potential benefits in the development of new treatments for cancer. However, its application in this field is still under investigation and requires further study to ensure safety and efficacy.
Used in Pharmaceutical Development:
Euphorbia factor L1 is used as a compound of interest in pharmaceutical development, where its cytotoxic properties are being explored for potential applications in creating new drugs or therapies, particularly for cancer treatment. The development of drug delivery systems and formulations that can mitigate its toxicity while harnessing its therapeutic potential is an ongoing area of research.
Used in Toxicological Studies:
Euphorbia factor L1 is used as a subject in toxicological studies to better understand its effects on biological systems and to develop methods for safe handling and management, ensuring the protection of humans and animals from its harmful effects.

Check Digit Verification of cas no

The CAS Registry Mumber 76376-43-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,3,7 and 6 respectively; the second part has 2 digits, 4 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 76376-43:
(7*7)+(6*6)+(5*3)+(4*7)+(3*6)+(2*4)+(1*3)=157
157 % 10 = 7
So 76376-43-7 is a valid CAS Registry Number.

76376-43-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Phosphononorvaline

1.2 Other means of identification

Product number -
Other names EUPATOROXIN,10-EPI

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76376-43-7 SDS

76376-43-7Downstream Products

76376-43-7Relevant academic research and scientific papers

Epoxidation studies on lathyra-6(17),12-dienes - Revised structure of the Euphorbia Factor L1

Appendino, Giovanni,Cravotto, Giancarlo,Jarevang, Tomas,Sterner, Olov

, p. 2933 - 2938 (2007/10/03)

As part of an investigation aimed at mimicking certain steps of the biogenesis of the polycyclic Euphorbia diterpenoids from macrocyclic precursors, the epoxidation of lathyrol and its esters with (peroxy/peroxo)metal complexes and non-metal (peracids and dioxiranes) oxidants was investigated. Treatment of lathyrol esters with methyl(trifluoromethyl)-dioxirane gave 6(17)β-epoxides as the only reaction products in very high yield. Conversely, lathyrol itself proved amenable to epoxidation only with the TBHP-VO(acac)2 protocol. Surprisingly, the reaction was not chemoselective, and also the enone double bond was epoxidized, eventually affording a rearranged compound of the 14(13→12)-abeo-lathyrane type. Based on the stereochemical course of the epoxidation of lathyrol esters and on NMR experiments on the natural product, the configuration at C-6 of the Euphorbia Factor L1 was revised, overturning a thirty-year misconception on the structure of this compound.

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