76379-02-7

Basic information

• Product Name: BOC-D-GLU(OME)-OH
• Synonyms: N-ALPHA-T-BUTOXYCARBONYL-D-GLUTAMIC ACID GAMMA-METHYL ESTER;BOC-D-GLU(OME)-OH;N-[(1,1-Dimethylethoxy)carbonyl]-D-glutamic acid 5-methyl ester compd. with N-cyclohexylcyclohexanamine;(Tert-Butoxy)Carbonyl D-Glu(OMe)-OH·DCHA
• CAS NO: 76379-02-7
• Molecular Formula: C₁₁H₁₉NO₆*C₁₂H₂₃N
• Molecular Weight: 261.27
• Mol File: 76379-02-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C
• CAS DataBase Reference: BOC-D-GLU(OME)-OH(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-D-GLU(OME)-OH(76379-02-7)
• EPA Substance Registry System: BOC-D-GLU(OME)-OH(76379-02-7)

Safety Data

• Hazardous Substances Data: 76379-02-7(Hazardous Substances Data)

Usage

General Description

BOC-D-GLU(OME)-OH is a chemical compound often used in peptide synthesis. It is a derivative of glutamic acid, an amino acid essential for protein synthesis and neurological function. The BOC (tert-butyloxycarbonyl) group is a protective group commonly used in peptide synthesis to prevent unwanted reactions at specific functional groups on the amino acid. The (OME) group indicates that a methoxy group is attached to the glutamic acid. Overall, BOC-D-GLU(OME)-OH is a key building block for creating peptides with specific sequence and structural properties, making it valuable in both biological and pharmaceutical research.

InChI:1S/C12H23N.C11H19NO6/c1-3-7-11(8-4-1)13-12-9-5-2-6-10-12;1-11(2,3)18-10(16)12-7(9(14)15)5-6-8(13)17-4/h11-13H,1-10H2;7H,5-6H2,1-4H3,(H,12,16)(H,14,15)/t;7-/m.0/s1

Upstream product

• 27025-22-5 D-glutamic acid-5-methyl ester; hydrochloride 
• 41840-28-2 S-tert-butoxycarbonyl-4,6-dimethyl-2-mercaptopyrimidine 
• 45214-91-3 N-α-(tert-butoxycarbonyl)-D-glutamic acid γ-methyl ester 
• 101-83-7 N-cyclohexyl-cyclohexanamine 

Downstream Products

• 34404-28-9 N-[(1,1-dimethylethoxy)carbonyl]-D-glutamic acid 
• 861658-15-3 1,5-dimethyl (2R)-2-[[(tert-butoxy)carbonyl]amino]pentanedioate 

Relevant articles and documents

Glucosamine peptide derivatives, their production and use

Novel glucosamine-peptide derivatives of the formula: STR1 wherein m is 0 or 1; n is 0 or an integer of 1 to 9; R is lower alkyl which may be substituted with hydroxyl, or aryl; R1 is hydrogen or acyl having an acyclic hydrocarbon group, the terminal of which may be substituted with a cyclic hydrocarbon group directly, via a carbonyl group or via an oxygen atom; provided that when R1 is hydrogen m is 1; R2 is hydrogen or lower alkyl which may form a ring by connecting its terminal with the α-nitrogen atom when n is 0, or hydrogen when n is an integer of 1 to 9; R3 is hydrogen or lower alkyl; R4 and R5 are each hydrogen or lower alkyl which may be substituted with hydroxyl or benzyloxyl; R6 is hydrogen or lower alkyl; R7 is alkyl which may be substituted with lower alkoxyl or aralkyl; R8 and R9 are each hydrogen, lower alkyl or aralkyl; and (D) and (L) each indicate configurations if their respective carbon atoms are asymmetric; or an acid addition salt thereof, have immunostimulatory activity.