76384-35-5Relevant academic research and scientific papers
Reaction of 2-Vinylpyridine and 2-(1-Methoxyvinyl)pyridine with Acrylic Acid Derivatives
Terent'ev, P. B.,Gulevich, Yu. V.,Gloriozov, I. P.,Kost, A. N.
, p. 1058 - 1060 (1980)
The regiospecificity of the reaction of 2-vinylpyridine and 2-(1-methoxyvinyl)pyridine with acrylonitrile and methyl acrylate was predicted on the basis of MO perturbation theory and was confirmed experimentally.The regioisomeric compositions of the reaction mixtures were studied by means of chromatographic mass spectrometry.
INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL
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Paragraph 0219, (2016/10/06)
The present invention provides compounds of Formula Ia and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and conditions associated with excessive salt and water retention.
INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL
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Page/Page column 97, (2013/03/26)
The present invention provides compounds of Formula Ia and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and conditions associated with excessive salt and water retention.
