76390-73-3Relevant academic research and scientific papers
Theoretical study of the mechanism of formation of 4-aminoisoxazoles. 2*. An unusual rearrangement of oximinonitriles
Kislyi,Danilova,Solkan
, p. 1042 - 1054 (2013/10/22)
The base-catalyzed cyclization of oximinonitriles in the presence of lithium ions leads to 4-aminoisoxazoles and, sometimes, to 5-aminooxazoles. Modeling using the density functional theory and the HF and MP2 methods indicated that both 4-aminoisoxazoles
4-Aminoisoxazoles by Thorpe Cyclization
Gewald, Karl,Bellmann, Peter,Jaensch, Hans-Joachim
, p. 1623 - 1629 (2007/10/02)
Cyclization of α-(acylmethoxyimino)nitriles 1 in the presence of lithium hydroxide yields 5-acyl-4-aminoisoxazoles 2.Compounds 2f and 2a can be converted into the isoxazolopyrimidone 3 and the isoxazolopyridine 4.
