76399-38-7Relevant academic research and scientific papers
The Selective Preparation of 1,4-Diaryl-6-methyl- and 1,6-Diaryl-4-methyl-2-(1H)pyrimidinones
Kashima, Choji,Katoh, Akira
, p. 913 - 915 (2007/10/02)
N-Phenylurea reacted with benzoylacetone derivatives (I) to give 1,4-diaryl-6-methyl-2-(1H)pyrimidinones (II) in addition to low yields of 1,6-diaryl-4-methyl-2-(1H)pyrimidinones (IV), while N-phenylthiourea afforded only 1,6-diaryl-4-methyl-2-(1H)pyrimidinethiones (III) in good yields.Further 1,6-diaryl-4-methyl-2-(1H)pyrimidinethiones (III) were succesfully converted in satisfactory yields into the corresponding 2-(1H)pyrimidinones (IV) by the treatment with methyl iodide in the presence of sodium methoxide in methanol at room temperature.
