76413-58-6Relevant academic research and scientific papers
Peptide-bond Formation, Chemoselective Acylation of Amino Acids, and Crosslinking Reaction between Amino Acids Utilizing a Functional Five-membered Heterocycle, 1,3-Thiazolidine-2-thione
Nagao, Yoshimitsu,Miyasaka, Tadayo,Seno, Kaoru,Fujita, Eiichi,Shibata, Daisuke,Doi, Etsushiro
, p. 2439 - 2446 (2007/10/02)
The monitored aminolysis of 3-acyl-1,3-thiazolidine-2-thiones has been extended to the peptide-bond formation, the chemoselective acylation of amino acids having multifunctional groups, and the crosslinking reaction between amino acids.
MONITORED AMINOLYSIS OF 3-ACYL-1,3-THIAZOLIDINE-2-THIONE WITH AMINO ACID AND ITS DERIVATIVE: PEPTIDE BOND FORMATION, CHEMOSELECTIVE ACYLATION, AND BRIDGING REACTION
Nagao, Yoshimitsu,Miyasaka, Tadayo,Seno, Kaoru,Yagi, Masahiro,Fujita, Eiichi
, p. 463 - 466 (2007/10/02)
As a new extention of the monitored aminolysis of 3-acyl-1,3-thiazolidine-2-thione, its applications to peptide bond formation, chemoselective acylation of amino acid, and bridging reaction on the enzyme model are reported.
Studies on Peptides. XCIV. Thiazoline-2-thione as a Carboxyl-activating Reagent for Peptide Synthesis
Yajima, Haruaki,Akaji, Kenichi,Hirota, Yoriko,Fujii, Nobutaka
, p. 3140 - 3142 (2007/10/02)
3-Acyl derivatives obtained from the DCC condensation of Nα-protected amino acids and thiazoline-2-thione were found to be useful for peptide synthesis, in the same way as active esters.Keywords---3-acylthiazoline-2-thione derivatives of N
