76437-02-0

Basic information

• Product Name: Silane, trimethyl[[1-(2-phenylethyl)-1-butenyl]oxy]-, (E)-
• CAS NO: 76437-02-0
• Molecular Formula: C15H24OSi
• Molecular Weight: 248.44
• Mol File: 76437-02-0.mol

Chemical Properties

• CAS DataBase Reference: Silane, trimethyl[[1-(2-phenylethyl)-1-butenyl]oxy]-, (E)-(CAS DataBase Reference)
• NIST Chemistry Reference: Silane, trimethyl[[1-(2-phenylethyl)-1-butenyl]oxy]-, (E)-(76437-02-0)
• EPA Substance Registry System: Silane, trimethyl[[1-(2-phenylethyl)-1-butenyl]oxy]-, (E)-(76437-02-0)

Safety Data

• Hazardous Substances Data: 76437-02-0(Hazardous Substances Data)

Upstream product

• 76436-92-5 6-phenyl-4-(trimethylsilyl)-2-hexen-4-ol 
• 61157-31-1 3-phenylpropionyltrimethylsilane 

Relevant articles and documents

BASE-INDUCED REARRANGEMENT OF 1-(TRIMETHYLSILYL)ALLYLIC ALCOHOLS. STEREO- AND REGIOSELECTIVE SYNTHESIS OF SILYL ENOL ETHERS THROUGH LITHIUM HOMOENOLATES.

1-(Trimethylsilyl)allylic alcohols have been prepared and their conversions to silyl enol ethers have been examined. Under appropriate conditions, lithium alkoxides of the above alcohols are in equilibrium with lithium homoenolates, 3-(trimethylsiloxy)allyllithiums, which react with alkyl iodides to give the silyl enol ethers of defined stereo- and regiochemistry. Further, a catalytic amount of butyllithium induces the rearrangement of the alcohols to yield the corresponding silyl enol ethers in a highly stereo- and regiocontrolled manner via self-protolysis. Equilibrium composition between lithium alkoxides and lithium homoenolates has been shown to be greatly influenced by the steric factors around alpha carbons of allylic alcohols.

STEREO- AND REGIO-SELECTIVE CONVERSION OF 1-TRIMETHYLSILYLALLYLIC ALCOHOLS INTO THE SILYL ENOL ETHERS CATALYZED BY BUTHYLLITHIUM

(Z)-Silyl enol ethers can be prepared selectively with complete regio-specificity by treating 1-trimethylsilylallylic alcohols with a catalytic amount of buthyllithium.