764648-44-4

Upstream product

• 132794-07-1 4-chloro-2,5-difluoro-benzoic acid 
• 508203-26-7 4-chloro-2,5-difluorobenzoic acid 
• 135748-35-5 4-chloro-2,5-difluoro-benzonitrile 

Downstream Products

• 885038-69-7 2-(4-chloro-2,5-difluorophenyl)-5,7-dihydrothieno[3,4-d]pyrimidin-4(3H)-one 
• 764648-50-2 2-(4-chloro-2,5-difluorophenyl)-6-ethylpyrimidin-4-one 
• 764648-49-9 2-(4-chloro-2,5-difluorophenyl)-6-methylpyrimidin-4-one 
• 885038-98-2 4-chloro-2-(4-chloro-2,5-difluorophenyl)-6,7-dihydro-5H-cyclopenta[d]pyrimidine 
• 885038-79-9 2-(4-chloro-2,5-difluorophenyl)-3,5,6,7-tetrahydro-4H-cyclopenta[d]pyrimidin-4-one 
• 1411734-64-9 {4-[2-(4-chloro-2,5-difluorophenyl)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}acetic acid 
• 885098-26-0 3-{1-[2-(4-chloro-2,5-difluorophenyl)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperidin-4-yl}propanoic acid 
• 1411734-52-5 ethyl {4-[2-(4-chloro-2,5-difluorophenyl)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperazin-1-yl}acetate 
• 885099-02-5 ethyl {1-[2-(4-chloro-2,5-difluorophenyl)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperidin-4-yl}acetate 
• 1411734-42-3 ethyl 1-[2-(4-chloro-2,5-difluorophenyl)-6,6-dioxido-5,7-dihydrothieno[3,4-d]pyrimidin-4-yl]piperidine-4-carboxylate 
• 885039-08-7 4-chloro-2-(4-chloro-2,5-difluorophenyl)-5,7-dihydrothieno[3,4-d]pyrimidine 6,6-dioxide 
• 885038-88-0 4-chloro-2-(4-chloro-2,5-difluorophenyl)-5,7-dihydrothieno[3,4-d]pyrimidine 
• 1191544-99-6 4-chloro-2-(4-chloro-2,5-difluorophenyl)-5,6,7,8-tetrahydroquinazoline 
• 1191544-96-3 2-(4-chloro-2,5-difluorophenyl)-5,6,7,8-tetrahydroquinazolin-4(3H)-one 

Relevant academic research and scientific papers

Discovery and biological evaluation of novel 4-amino-2-phenylpyrimidine derivatives as potent and orally active GPR119 agonists

Novel 4-amino-2-phenylpyrimidine derivatives were synthesized and evaluated as GPR119 agonists. Optimization of the substituents on the phenyl ring at the 2-position and the amino group at the 4-position led to the identification of 3,4-dihalogenated and

PYRIMIDINE DERIVATIVE CONDENSED WITH NON-AROMATIC RING

There are provided new pyrimidine derivatives condensed with a non-aromatic ring selected from dihydrothiophene, dihydrofuran, cycloalkane moiety, and the like or pharmaceutically acceptable salts thereof; and a pharmaceutical composition comprising said