764661-20-3Relevant academic research and scientific papers
Pt-based chiral organotin modified heterogeneous catalysts for the enantioselective hydrogenation of 3,4-hexanedione
Vetere, Virginia,Faraoni, María B.,Podestá, Julio C.,Casella, Mónica L.
, p. 209 - 214 (2013/02/23)
In this paper we have studied the liquid-phase enantioselective hydrogenation of 3,4-hexanedione using Pt-based catalysts, modified with chiral organotin compounds derived from the (-)-menthyl group: (-)-Pt-MenSnBu 3 and (-)-Men3Sn-Sn-(-)-Men3. The organotin chiral modifiers were carefully synthesized and characterized in order to obtain optically pure compounds. The catalysts were prepared through a controlled surface reaction between the supported transition metal and the organometallic compound, using techniques derived from Surface Organometallic Chemistry on Metals (SOMC/M). The organobimetallic catalytic systems were found to be active and enantioselective in the hydrogenation of 3,4-hexanedione, yielding an enantiomeric excess of 25-27% for 4-hydroxy-3-hexanone.
