76469-32-4Relevant academic research and scientific papers
BEHAVIOR OF 2- AND 4-CYCLOPROPYLPHENYL ETHERS DURING NITRATION WITH NITRIC ACID IN ACETIC ANHYDRIDE
Mochalov, S. S.,Karpova, V. V.,Shabarov, Yu. S.
, p. 1780 - 1785 (2007/10/02)
During the nitration of 4-cyclopropyl phenyl ethers dilute nitric acid in acetic anhydride formal dealkylation (or dearylation) is realized with substituent entry of the nitro group into the para-substituted phenol which forms.Under analogous conditions the behavior of the corresponding ortho-substituted phenyl ethers depends both on the steric limitations created by the aroxyl (or alkoxyl) fragment and on its polar effect.In the reaction of cyclopropylphenyl ethers with concentrated nitric acid in acetic anhydride the formation of nitrophenols is hardly observed at all.
