764696-71-1Relevant academic research and scientific papers
Influence of substitution at the 5α-Position on the side chain conformation of glucopyranosides
Rajasekaran, Parasuraman,Pirrone, Michael G.,Crich, David
, (2021)
We describe the preparation of methyl 5α-methyl-α-D-glucopyranoside and of 5α-fluoro-β-D-glucopyranose per acetate and the NMR-based conformational analysis of their side chains. Both the 5α-methyl and 5α-fluoro substituents increase the population of the
Synthesis of an unusual branched-chain sugar, 5-C-methyl-L-idopyranose for SAR studies of pyranmycins: Implication for the future design of aminoglycoside antibiotics
Wang, Jinhua,Li, Jie,Czyryca, Przemyslaw G.,Chang, Huiwen,Kao, Jeff,Tom Chang, Cheng-Wei
, p. 4389 - 4393 (2007/10/03)
The syntheses of a challenging branched-chain sugar and several l-sugars have been accomplished. Their application in the studies of the antibacterial activity of pyranmycins is reported, which could provide new strategies for the future design of aminoglycoside antibiotics. The syntheses of a challenging branched-chain sugar and several l-sugars have been accomplished. Their application in studies of the antibacterial activity of pyranmycins is reported, which could provide new strategies for the future design of aminoglycoside antibiotics.
