Cas 764718-76-5,4'-Trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-{(R)-3-[3-(4-chloro-phenyl)-3-methyl-butylamino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-methyl-amide

764718-76-5

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Basic information

Product Name: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-{(R)-3-[3-(4-chloro-phenyl)-3-methyl-butylamino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-methyl-amide
Synonyms: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-{(R)-3-[3-(4-chloro-phenyl)-3-methyl-butylamino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-methyl-amide
CAS NO:764718-76-5
Molecular Formula:
Molecular Weight: 641.176
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-{(R)-3-[3-(4-chloro-phenyl)-3-methyl-butylamino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-methyl-amide(CAS DataBase Reference)
NIST Chemistry Reference: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-{(R)-3-[3-(4-chloro-phenyl)-3-methyl-butylamino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-methyl-amide(764718-76-5)
EPA Substance Registry System: 4'-Trifluoromethyl-biphenyl-4-carboxylic acid ((S)-1-{(R)-3-[3-(4-chloro-phenyl)-3-methyl-butylamino]-pyrrolidine-1-carbonyl}-pyrrolidin-3-yl)-methyl-amide(764718-76-5)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 764718-76-5(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 764718-76-5 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,4,7,1 and 8 respectively; the second part has 2 digits, 7 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 764718-76:
(8*7)+(7*6)+(6*4)+(5*7)+(4*1)+(3*8)+(2*7)+(1*6)=205
205 % 10 = 5
So 764718-76-5 is a valid CAS Registry Number.

764718-76-5Upstream product

91427-13-3 3-(4-chlorophenyl)-3-methylbutyraldehyde

764718-76-5Downstream Products

764718-76-5Relevant academic research and scientific papers

Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 1

Rowbottom, Martin W.,Vickers, Troy D.,Dyck, Brian,Grey, Jonathan,Tamiya, Junko,Zhang, Mingzhu,Kiankarimi, Mehrak,Wu, Dongpei,Dwight, Wesley,Wade, Warren S.,Schwarz, David,Heise, Christopher E.,Madan, Ajay,Fisher, Andrew,Petroski, Robert,Goodfellow, Val S.

, p. 4450 - 4457 (2007/10/03)

The design, synthesis, and SAR of a series of retro bis-aminopyrrolidine ureas are described. Compounds from this series exhibited potent binding affinity and functional activity at MCH-R1, and good oral bioavailability in rat.

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