76478-14-3

Upstream product

• 4344-42-7 rhodamine B 
• 64-17-5 ethanol 

Downstream Products

• 74317-53-6 rhodamine B hydrazide 

Relevant academic research and scientific papers

Chelation enhanced fluorescence of rhodamine based novel organic nanoparticles for selective detection of mercury ions in aqueous medium and intracellular cell imaging

A simple, quick and useful reprecipitation method was used to prepare rhodamine based fluorescent nanoparticles. The characterization techniques such as zeta-particle sizer and scanning electron microscopy were studied to investigate the formation of desired nanoparticles FONs-RSB along with its aqueous stability, surface charge, particle size, and morphological features. The comparative optical properties between parent molecule RSB and FONs-RSB were examined using absorption and fluorescence studies. The sphere morphology of FONs-RSB having 82 nm particle size and negative zeta potential (?33.5 mV) showed selective and sensitive interaction with only Hg2+ amongst the series of metal ion studied which was revealed by florescence titration results. The interaction between FONs-RSB and Hg2+ leads to enhance the fluorescence of FONs-RSB is because of chelation enhanced fluorescence (CHEF) phenomenon. The interference of foreign metal ions was found to be unaffected to the fluorescence enhancement induced by Hg2+. The binding stoichiometry and binding constant were evaluated using Job's and modified Benesi-Hildebrand plot. The mechanism of binding interaction and nature of complexation were analyzed using Infrared (IR), Nuclear Magnetic Resonance (NMR), absorption and fluorescence lifetime titrations in the absence and presence of a variable amount of Hg2+ to FONs-RSB. Further, the reaction product of the sensing process in the present investigation was examined using mass analysis. The detection limits calculated using the present method were found to be 1.729 ng/mL (8.619 nM) and 1.68 ng/mL when linear concentration of Hg2+ additions were 0?2 μg/mL and 0?100 ng/mL, respectively. The practical application of the present method involves the quantitative determination of Hg2+ in environmental samples collected from the local campus and intracellular cell imaging of Hg2+ using A375 living cells with non-toxic behavior.

Xanthene derivative and a production process of the same

This invention relates to a xanthene derivative that develops color on oxidation, so that it is favorably used for a photoresist, a PS plate or a proofing agent. The xanthene derivative, which has the following structural formula (I), is produced by putting a fluoran derivative represented by the following structural formula (II) to an esterification reaction and then to a reduction reaction. STR1 In the above formulae R1 and R2 independently stand for hydrogen, an alkyl radical with 1 to 8 carbon atoms, a tetrahydrofurfuryl radical, a substitued or an unsubstituted phenyl radical, a substituted or an unsubstituted benzyl radical or a cyclic alkyl radical; in addition, R1 and R2 are able to form a ring in pairs. R3 and R6 independently stand for hydrogen, chlorine, fluorine, a lower alkyl radical or a lower alkoxy radical. R4 and R5 independently stand for hydrogen, chlorine, fluorine, a lower alkyl radical, a lower alkoxy radical, a lower alkoxyalkyl radical, a substituted or an unsubstituted phenyl radical, a substituted or an unsubstituted benzyl radical, an amino radical, a N-substituted or N,N-substituted amino radical or a cyclic alkyl radical; in addition, R3 and R4, R4 and R5, and R5 and R6 are able to form a ring in pairs respectively. R7 stands for an alkyl radical, a substituted or an unsubstituted phenyl radical or a substituted or an unsubstituted benzyl radical. X stands for hydrogen, chlorine, fluorine, bromine, a nitro radical, a lower alkyl radical or a lower alkylamino radical; and n stands for an integer from 1 to 4 inclusive.