76491-48-0

Basic information

• Product Name: tert-butyloxycarbonylalanyl-D-isoglutaminyl-N^ε-benzyloxycarbonyllysyl-D-alanine
• CAS NO: 76491-48-0
• Molecular Weight: 650.729
• Mol File: 76491-48-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyloxycarbonylalanyl-D-isoglutaminyl-N^ε-benzyloxycarbonyllysyl-D-alanine(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyloxycarbonylalanyl-D-isoglutaminyl-N^ε-benzyloxycarbonyllysyl-D-alanine(76491-48-0)
• EPA Substance Registry System: tert-butyloxycarbonylalanyl-D-isoglutaminyl-N^ε-benzyloxycarbonyllysyl-D-alanine(76491-48-0)

Safety Data

• Hazardous Substances Data: 76491-48-0(Hazardous Substances Data)

Upstream product

• 76491-42-4 tert-butyloxycarbonyl-N^ε-benzyloxycarbonyllysyl-D-alanine methyl ester 
• 63648-75-9 D-isoglutamine hydrobromide 
• 18814-50-1 (R)-5-amino-4-{(S)-2-[(tert-butoxycarbonyl)amino]propanamido}-5-oxopentanoic acid 
• 2389-45-9 Boc-Lys(Z)-OH 
• 2483-49-0 tert-butyloxycarbonyl-L-alanine p-nitrophenyl ester 
• 76491-47-9 tert-butyloxycarbonylalanyl-D-isoglutaminyl-N^ε-benzyloxycarbonyllysyl-D-alanine methyl ester 

Relevant articles and documents

SYNTHESIS OF PEPTIDES, GLYCO DERIVATIVES AND GLYCOPEPTIDES FROM BACTERIAL CELL WALLS

Synthesis in solution and in solid phase was used to prepare alanyl-D-isoglutamine (VI), alanyl-D-isoglutaminyl-Nε-p-toluenesulfonyl-lysyl-D-alanine methyl ester (XIII), alanyl-D-isoglutaminyl-Nε-acetyl-lysyl-D-alanine methyl ester (XIV), alanyl-D-isoglutaminyl-Nε-acetyl-lysyl-D-alanyl-pentaglycine methyl ester and amide (XXXI, XXXII), methyl ester (XXXV), methyl ester (XXXVII), N-acetylmuramyl-alanyl-D-isoglutaminyl-Nε-acetyl-lysyl-D-alanyl-pentaglycine amide (XXXIX), methyl ester (XLI), and methyl ester (XLIII).Thetetrapeptides, nonapeptides, and tridecapeptides show a pronounced pyrogenic effect.Imunoadjuvant activity was observed not only with the glycopeptides but also with nonapeptide XXXI.