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15,16-Dir-8(17),11-labdadien-13-one is a labdane-type diterpenoid compound belonging to the diterpene class. It is found in various plant species, particularly isolated from the root of the Rhodiola crenulata plant. Characterized by a unique chemical structure with a 15,16-double bond, an 8(17)-enone group, and a 11-labdadiene skeleton, 15,16-Dir-8(17),11-labdadien-13-one has garnered interest due to its potential biological activities, such as anti-inflammatory, anti-cancer, and neuroprotective properties. Its complex structure and medicinal potential make it a significant subject of research in the realms of natural products and medicinal chemistry.

76497-69-3

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76497-69-3 Usage

Uses

Used in Pharmaceutical Industry:
15,16-Dir-8(17),11-labdadien-13-one is used as a pharmaceutical agent for its potential anti-inflammatory properties, making it a candidate for the development of treatments targeting inflammation-related conditions.
Used in Oncology Research:
In the field of oncology, 15,16-Dir-8(17),11-labdadien-13-one is utilized as a subject of research for its anti-cancer properties, with potential applications in the discovery and development of novel cancer therapeutics.
Used in Neuroprotective Therapies:
15,16-Dir-8(17),11-labdadien-13-one is employed as a neuroprotective agent in research aimed at finding treatments for neurodegenerative diseases, given its potential to protect neurons and mitigate neuronal damage.
Used in Natural Products Chemistry:
As a complex natural product, 15,16-Dir-8(17),11-labdadien-13-one is used in chemical research to understand its structure-activity relationships, which can lead to the optimization of its medicinal properties and the creation of new compounds with improved efficacy.
Used in Medicinal Chemistry:
In medicinal chemistry, 15,16-Dir-8(17),11-labdadien-13-one serves as a lead compound for the design and synthesis of new pharmaceuticals, leveraging its biological activities to address various medical conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 76497-69-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,4,9 and 7 respectively; the second part has 2 digits, 6 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 76497-69:
(7*7)+(6*6)+(5*4)+(4*9)+(3*7)+(2*6)+(1*9)=183
183 % 10 = 3
So 76497-69-3 is a valid CAS Registry Number.

76497-69-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (3E)-4-[(1S,4aS,8aS)-5,5,8a-Trimethyl-2-methylenedecahydro-1-naph thalenyl]-3-buten-2-one

1.2 Other means of identification

Product number -
Other names (3E)-4-[(1S,4aS,8aS)-5,5,8a-Trimethyl-2-methylenedecahydro-1-naphthalenyl]-3-buten-2-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76497-69-3 SDS

76497-69-3Downstream Products

76497-69-3Relevant academic research and scientific papers

Photosensitized Oxygenation of Labda-8(17),12-diene, Labda-8(17),13-diene, and the Biformenes. Synthesis of Pumiloxide

Mohanraj, Subramaniam,Herz, Werner

, p. 1362 - 1366 (2007/10/02)

Reactions of the title compounds with singlet oxygen were studied.In labda-8(17),12-diene (2; 7:3 mixture of E and Z isomers), syn addition leading to 7 (58percent) was predominant.Smaller amounts of 8 (20percent) by syn addition to (E)-2 or anti addition to (Z)-2, 9 (5percent), 10 (2,5percent), and 11(1.5percent) were also formed. (E)-Labda-8(17),13-diene ((E)-3) gave 29percent 12 and 40percent 13 by syn addition, whereas (Z)-3 gave 57percent 12 by syn addition and 19percent 13 by anti addition.In trans-biformene (5) syn attack at C-12 to give 15 (27percent), 16 (10percent), 18 (12percent), and 19 (4percent) was greatly preferred to syn attack at C-13 to give 17 (6percent).In cis-biformene (6) syn attack at C-13 to give 17 (39percent) predominated slightly over anti attack at C-12 to give 15 (13percent), 16 (8percent), 18 (4percent), and 19 (4percent).Diels-Alder reactions with singlet oxygen leading to epidioxides 20 and 21 were relatively unimportant (7percent from 5, 5percent from 6).The epidioxides were converted to the naturally occurring furanolabdane pumiloxide (22).

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