765-39-9

Basic information

• Product Name: 1-AMINOPYRROLE
• Synonyms: 1-AMINOPYRROLE;1H-Pyrrol-1-amine;1-Amino-1H-pyrrole;pyrrol-1-amine;pyrrol-1-ylamine;1-AMINOPYRROLE（freebase);LHTE
• CAS NO: 765-39-9
• Molecular Formula: C₄H₆N₂
• Molecular Weight: 82.1
• Product Categories: Functional Materials;Pyrroles (for Conduting Polymer Research);Reagents for Conducting Polymer Research
• Mol File: 765-39-9.mol
• Article Data: 16

Chemical Properties

• Melting Point: 77-78 °C
• Boiling Point: 174
• Flash Point: 36 °C
• Appearance: /
• Density: 1,06 g/cm3
• Vapor Pressure: 0.797mmHg at 25°C
• Refractive Index: 1.538
• Storage Temp.: Refrigerator
• PKA: -2.35±0.70(Predicted)
• CAS DataBase Reference: 1-AMINOPYRROLE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-AMINOPYRROLE(765-39-9)
• EPA Substance Registry System: 1-AMINOPYRROLE(765-39-9)

Safety Data

• Hazard Codes: C
• Statements: 10-34-22
• Safety Statements: 16-26-36-45-36/37/39
• RIDADR: 2734
• HazardClass: 8
• PackingGroup: Ⅲ
• Hazardous Substances Data: 765-39-9(Hazardous Substances Data)

Usage

Uses

1H-Pyrrol-1-amine is used in preparation of reproducible and high-temp. thermosetting flame-retardant resin.

InChI:InChI=1/C4H6N2/c5-6-3-1-2-4-6/h1-4H,5H2

Upstream product

• 7531-52-4 L-prolinamide 
• 109-97-7 pyrrole 
• 885-12-1 1-phthalimidopyrrole 

Downstream Products

• 937046-95-2 N-(1H-pyrrol-1-yl)-carbamic acid tert-butyl ester 
• 343615-78-1 1-(Pyrrol-1-ylsulfamoyl)-piperidine-2S-carboxylic acid 4-phenylbutyl ester 
• 7631-86-9 SiO₂ 
• 274-55-5 5-Azaindolizin 
• 149543-55-5 (S)-2-<(Benzyloxycarbonyl)amino>-3-hydroxy-N-(1-pyrrolyl)propanamide 
• 1357159-02-4 2-phenyl-N-(1H-pyrrol-1-yl)acetamide 
• 1264670-29-2 2-phenyl-1-pyrrol-1-yl-1H-indole 
• 1246847-11-9 ethyl 4-phenylpyrrolo[2,1-f]pyridazine-2-carboxylate 
• 1246847-10-8 ethyl 4-(4-bromophenyl)pyrrolo[2,1-f]pyridazine-2-carboxylate 
• 156335-37-4 ethyl 1,4-dihydro-4-oxopyrrolo<1,2-b>pyridazine-3-carboxylate 
• 929558-41-8 ethyl 6-[N-(1H-pyrrol-1-yl)sulfamoyl]-1-cyclohexene-1-carboxylate 
• 55872-89-4 1-(4-nitrosophenylamino)pyrrole 
• 92064-94-3 1-(2-Phenylpropyl)-4-(1H-pyrrol-1-yl)-aminopiperidine 
• 92064-79-4 1-[2-(4-chlorophenyl)ethyl]-4-(1H-pyrrol-1-yl)aminopiperidine 

Relevant articles and documents

HETEROCYCLIC COMPOUNDS

The present invention relates to compounds of the general formula (1) wherein the variables are defined as given in the description and claims. The invention further relates to uses of and to, processes and intermediates related to compounds of the general formula (I), wherein Q is wherein the substituents of I, Ia and Ib are as defined in description and claims.

PYRROLOPYRIDAZINE JAK3 INHIBITORS AND THEIR USE FOR THE TREATMENT OF INFLAMMATORY AND AUTOIMMUNE DISEASES

Disclosed are compounds of Formula (I), and pharmaceutically acceptable salts thereof. The compounds of formula (I) inhibit tyrosine kinase activity of JAK3, thereby making them useful for the treatment of inflammatory and autoimmune diseases.

1,1′-Bipyrroles: Synthesis and stereochemistry

(Chemical Equation Presented) 1,1′-Bipyrrole is synthesized in four steps from hydrazine. A colorless solid, mp 52°C, it sublimes readily at room temperature and forms X-ray quality crystals in which the rings are not coplanar but are nearly orthogonal.