765-95-7Relevant academic research and scientific papers
Activation of the hypervalent fluoroiodane reagent by hydrogen bonding to hexafluoroisopropanol
Minhas, Harsimran K.,Riley, William,Stuart, Alison M.,Urbonaite, Martyna
supporting information, p. 7170 - 7173 (2018/10/24)
Hexafluoroisopropan-2-ol (HFIP) is an excellent solvent for promoting fluorinations with the hypervalent fluoroiodane reagent 1 and crucially, it removes the need for transition metals or TREAT-HF activators. The fluoroiodane reagent 1 was used in HFIP to monofluorinate 1,3-ketoesters and to fluorocyclise unsaturated carboxylic acids in excellent yields under mild reaction conditions.
Fluorocyclization of unsaturated alcohols and carboxylic acids by iodotoluene difluoride and amine-HF complexes
Sawaguchi, Masanori,Hara, Shoji,Fukuhara, Tsuyoshi,Yoneda, Norihiko
, p. 277 - 280 (2007/10/03)
In the presence of amine-HF complexes, iodotoluene difluoride reacted with unsaturated alcohols and carboxylic acids to give cyclic fluoroethers and fluorolactones, respectively.
