76511-72-3Relevant academic research and scientific papers
Cu(OAc)2·H2O-catalyzed N-arylation of nitrogen-containing heterocycles
Xu, Zhong-Lin,Li, Hong-Xi,Ren, Zhi-Gang,Du, Wei-Yuan,Xu, Wei-Chang,Lang, Jian-Ping
supporting information; experimental part, p. 5282 - 5288 (2011/08/04)
In the absence of any additional ligands, the efficient N-arylation of nitrogen-containing heterocycles with aryl iodides catalyzed by relative low catalyst amount of Cu(OAc)2·H2O was developed. This simple catalytic system is involved in the C-N cross-coupling reaction and works for a variety of pyrazole, pyrrole, imidazole, triazole, indole, benzoimidazole, benzotriazole, carbazole, and anilines as well as aryl iodides with different electronic properties. Highly efficient copper(II)-catalyzed N-arylation protocol was established.
