76512-22-6Relevant articles and documents
3-Amino-5-(hydroxy- and/or aminophenyl)-6-(lower-alkyl)-2(1H)-pyridinones and cardiotonic use thereof
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, (2008/06/13)
1-R1 -3-amino-5-(3-R'-4-R"-phenyl)-6-R-2(1H)-pyridinones or salts thereof, which are useful as cardiotonics, where R1 is hydrogen, lower-alkyl, or lower-hydroxyalkyl, R is hydrogen or lower-alkyl, and, R' and R" are each hydrogen, hy
5-Substituted pyranone compounds and their use as pharmaceuticals to treat an immediate hypersensitivity condition
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, (2008/06/13)
Compounds are described of the formula STR1 in which R1 is COOR5, CONHR5, cyano, 5-tetrazolyl or 5-tetrazolylaminocarbonyl, where R5 is hydrogen or C1-6 alkyl; R2 is hydrogen or C1-6 alkyl; R3 is a group of the formula where m is O or 1, Z is O, S, SO, SO2 or CO, and R6 phenyl optionally substituted by one or more group selected from halogen, C1-4 alkyl, C3-6 cycloalkyl, C1-4 alkoxy, benzyloxy, hydroxy, nitro, C1-4 alkylthio, C1-4 alkylsulphinyl, C1-4 alkylsulphonyl, amino and NHR7 where R7 is C2-6 acyl; and R4 is hydrogen, C1-6 alkyl or halogen; and salts thereof. These compounds have pharmaceutical properties and in particular are useful in the treatment of immediate hypersensitivity conditions such as asthma.