76513-99-0

Basic information

• Product Name: 5-(trifluoromethyl)-3',5'-di-O-trityl-2'-deoxyuridine
• Synonyms: 5-(trifluoromethyl)-3',5'-di-O-trityl-2'-deoxyuridine
• CAS NO: 76513-99-0
• Molecular Weight: 780.843
• Mol File: 76513-99-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-(trifluoromethyl)-3',5'-di-O-trityl-2'-deoxyuridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-(trifluoromethyl)-3',5'-di-O-trityl-2'-deoxyuridine(76513-99-0)
• EPA Substance Registry System: 5-(trifluoromethyl)-3',5'-di-O-trityl-2'-deoxyuridine(76513-99-0)

Safety Data

• Hazardous Substances Data: 76513-99-0(Hazardous Substances Data)

Upstream product

• 2314-97-8 iodotrifluoromethane 
• 76513-98-9 3',5'-di-O-trityl-5-iodo-2'-deoxyuridine 

Downstream Products

• 70-00-8 2'-deoxy-5-trifluoromethyluridine 

Relevant articles and documents

Studies on Organic Fluorine Compounds. Part 35. Trifluoromethylation of Pyrimidine- and Purine-nucleosides with Trifluoromethyl-Copper Complex

Halogenated nucleoside derivatives were trifluoromethylated using a solution of a trifluoromethyl-copper complex, which was prepared by shaking trifluoromethyl iodide and copper powder in hexamethylphosphoric triamide and filtering off the excess of copper powder.The following trifluoromethylated nucleosides were obtained in moderate to good yields: 5-trifluoromethyl-uridine, -deoxyuridine, -cytidine, -deoxycytidine, and arabinosylcytosine; 8-trifluoromethyl-adenosine, -deoxyadenosine, and -inosine; and 6-trifluoromethylribofuranosylpurine.This procedure offers simple synthesis of many trifluoromethyl compounds.