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H-LEU-VAL-TYR-AMC is a fluorogenic substrate specifically designed for use in enzymatic assays to measure the activity of certain proteases, such as caspases and chymotrypsin-like proteasomes. It is characterized by its ability to release a fluorescent 7-amino-4-methylcoumarin (AMC) group upon cleavage by these proteases, which can be easily detected and quantified using fluorescence spectroscopy. The high specificity and sensitivity of H-LEU-VAL-TYR-AMC make it a valuable tool for studying protease activity and for developing potential therapies targeting these enzymes.

76524-85-1

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76524-85-1 Usage

Uses

Used in Enzymatic Assays:
H-LEU-VAL-TYR-AMC is used as a fluorogenic substrate for measuring the activity of specific proteases, such as caspases and chymotrypsin-like proteasomes. The release of the fluorescent AMC group upon protease cleavage allows for the detection and quantification of protease activity in various biological samples.
Used in Research and Development:
H-LEU-VAL-TYR-AMC is used as a research tool for studying the activity and function of proteases in different biological processes. Its high specificity and sensitivity make it an ideal candidate for investigating the role of proteases in various diseases and conditions, as well as for developing potential therapies targeting these enzymes.
Used in Drug Discovery and Development:
H-LEU-VAL-TYR-AMC is used as a screening tool in drug discovery and development to identify and evaluate potential inhibitors or activators of proteases. By monitoring the activity of these enzymes in the presence of different compounds, researchers can gain insights into the mechanisms of action and potential therapeutic effects of these compounds.
Used in Diagnostic Applications:
H-LEU-VAL-TYR-AMC can be used as a diagnostic tool to detect and monitor the activity of proteases in clinical samples. The ability to measure protease activity accurately and sensitively can aid in the diagnosis and prognosis of various diseases and conditions, as well as in monitoring the effectiveness of treatments.
Used in Quality Control and Validation:
H-LEU-VAL-TYR-AMC is used in quality control and validation processes to ensure the accuracy and reliability of protease activity measurements. By providing a consistent and sensitive substrate for protease cleavage, H-LEU-VAL-TYR-AMC helps to standardize enzymatic assays and validate the results obtained from different laboratories and research groups.

Check Digit Verification of cas no

The CAS Registry Mumber 76524-85-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,5,2 and 4 respectively; the second part has 2 digits, 8 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 76524-85:
(7*7)+(6*6)+(5*5)+(4*2)+(3*4)+(2*8)+(1*5)=151
151 % 10 = 1
So 76524-85-1 is a valid CAS Registry Number.

76524-85-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name H-LEU-VAL-TYR-AMC

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76524-85-1 SDS

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