76526-96-0Relevant academic research and scientific papers
One-pot metal-free synthesis of highly substituted pyrroles from 2-acetyl-3-methylene-1,4-dicarbonyl compounds and primary amines via TBHP and activated carbon oxidative aromatization of dihydropyrrole
Yang, Wei,Zhou, Yu,Sun, Haifeng,Zhang, Lei,Zhao, Fei,Liu, Hong
, p. 15007 - 15010 (2014)
A metal-free one-pot cascade process for the synthesis of 1,2,3,4-tetrasubstituted pyrroles via a tandem enamine, aza-Michael addition and TBHP, activated carbon oxidative aromatization is reported. This strategy features the formation of two C-N bonds in moderate to excellent yields and a broad substrate tolerance. the Partner Organisations 2014.
SYNTHESIS OF PYRROLOINDOLES: VILSMEIER FORMYLATION OF SOME 3-METHYLINDOL-2-YL KETONES AND 3(3-METHYLINDOL-2-YL)PROPENOIC ESTER
Kazembe, Takawira, C.-G,Taylor, Deryck, A.
, p. 2125 - 2132 (2007/10/02)
3-Methylindol-2-yl methyl ketone reacted with phosphoryl chloride in dimethylformamide to give 3-chloro-3(3-methylindol-2-yl)propenal (4). 2-Carbomethoxy- and 2-carbethoxy-1-chloro-9H-pyrroloindol-9-ylidene acetaldehyde (10a and b) were formed by r
