76527-08-7

Basic information

• Product Name: Butanoic acid, 4,4,4-trichloro-3-methyl-, (R)-
• CAS NO: 76527-08-7
• Molecular Formula: C5H7Cl3O2
• Molecular Weight: 205.468
• Mol File: 76527-08-7.mol

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 4,4,4-trichloro-3-methyl-, (R)-(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4,4,4-trichloro-3-methyl-, (R)-(76527-08-7)
• EPA Substance Registry System: Butanoic acid, 4,4,4-trichloro-3-methyl-, (R)-(76527-08-7)

Safety Data

• Hazardous Substances Data: 76527-08-7(Hazardous Substances Data)

Upstream product

• 102917-45-3 (S)-4,4,4-Trichloro-3-methyl-butyric acid (1R,2S,3R,4S)-3-[benzenesulfonyl-(3,5-dimethyl-phenyl)-amino]-1,7,7-trimethyl-bicyclo[2.2.1]hept-2-yl ester 
• 65647-65-6 isodysidenin 
• 65647-65-6 dysidenin 
• 70-34-8 2,4-Dinitrofluorobenzene 

Downstream Products

• 1207193-62-1 C₁₄H₁₆Cl₃NO₃ 
• 1207193-63-2 C₁₄H₁₆Cl₃NO₃ 
• 95187-90-9 (R)-N-((S)-1-phenylaethyl)-3-(trichlormethyl)butyramid 
• 76527-12-3 (R)-(+)-ethyl 2-(4-bromophenyl)-2-oxo-3-methyl-4,4,4-trichlorobutanoate 
• 93714-83-1 (R,R)-(+)-N-<(1phenyl)ethyl>-3-methyl-4,4,4-trichlorobutanamide 
• 65647-65-6 dysidenin 
• 91279-96-8 dysidin 
• 76527-12-3 (S)-4,4,4-Trichloro-3-methyl-butyric acid 2-(4-bromo-phenyl)-2-oxo-ethyl ester 

Relevant articles and documents

SYNTHESIS OF ENANTIOMERICALLY PURE (S)-3-TRICHLOROMETHYLBUTYRIC ACID VIA ASYMMETRIC CONJUGATE ADDITION OF TRICHLOROMETHYL METAL COMPOUNDS TO A CHIRAL ENOATE. ACTIVATION EFFECT OF A SULFONYLAMINO GROUP.

(+)(S)-3-Trichloromethylbutyric acid, a building block for synthesis of various marine natural products, can be prepared via 99:1 stereoselective conjugate addition of Cl3CMgCl to the crotonate of a chiral auxiliary containing a sulfonylamino substituent.

CHEMICAL STUDIES OF MARINE INVERTEBRATES-XLII THE RELATIVE AND ABSOLUTE CONFIGURATION OF DYSIDENIN

The relative and absolute configuration of dysidenin has been determined by chemical correlation between dysidenin, isodysidenin and their respective dechlorinated derivatives.