76527-23-6

Basic information

• Product Name: 2-Diazo-1-(2-phenyl-oxiranyl)-ethanone
• Synonyms: 2-Diazo-1-(2-phenyl-oxiranyl)-ethanone
• CAS NO: 76527-23-6
• Molecular Weight: 188.186
• Mol File: 76527-23-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Diazo-1-(2-phenyl-oxiranyl)-ethanone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Diazo-1-(2-phenyl-oxiranyl)-ethanone(76527-23-6)
• EPA Substance Registry System: 2-Diazo-1-(2-phenyl-oxiranyl)-ethanone(76527-23-6)

Safety Data

• Hazardous Substances Data: 76527-23-6(Hazardous Substances Data)

Upstream product

• 98324-46-0 potassium α-phenylglycidate 
• 24568-17-0 sodium a-phenylglycidate 
• 186581-53-3 diazomethane 

Downstream Products

• 145762-42-1 2-chloromethyl-2-phenyl-oxetan-3-one 

Relevant articles and documents

SYNTHESIS OF α,β-EPOXY DIAZOMETHYL KETONES

The preparation of eighteen epoxy diazomethyl ketones 1 is described.Two general methods were developed.Firstly, treatment of the mixed anhydrides of glycidic acids and carbonic acid ester with diazomethane led to the title compounds in yields ranging from 17-74 percent.Secondly, glycidyl chlorides which were obtained from sodium glycidates and oxalyl chloride, gave the desired products upon treatment with diazomethane ( yields 60-74 percent).The required α,β-epoxy carboxylic esters were prepared by Darzens condensation and epoxidation of α,β-unsaturated esters, but in some cases also by reaction of α-oxo carboxylic esters with diazomethane.