765292-71-5

Basic information

• Product Name: 2-Butanone, 1-[2-[(1,1-dimethylethyl)thio]phenyl]-4-phenyl-
• CAS NO: 765292-71-5
• Molecular Formula: C20H24OS
• Molecular Weight: 312.476
• Mol File: 765292-71-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Butanone, 1-[2-[(1,1-dimethylethyl)thio]phenyl]-4-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Butanone, 1-[2-[(1,1-dimethylethyl)thio]phenyl]-4-phenyl-(765292-71-5)
• EPA Substance Registry System: 2-Butanone, 1-[2-[(1,1-dimethylethyl)thio]phenyl]-4-phenyl-(765292-71-5)

Safety Data

• Hazardous Substances Data: 765292-71-5(Hazardous Substances Data)

Upstream product

• 765292-68-0 2-[2'-(tert-butylsulfanyl)phenyl]-1,3-dithiane 
• 89-98-5 2-chloro-benzaldehyde 
• 65924-65-4 2-(tert-butylthio)benzaldehyde 

Downstream Products

• 28540-48-9 2-(2'-phenylethyl)benzo[b]thiophene 

Relevant articles and documents

Titanium reagents for the synthesis of 2-substituted benzo[b]thiophenes on the solid phase

Titanium(IV) benzylidenes (Schrock carbenes) bearing a masked sulfur nucleophile in the ortho position were generated from thioacetals with use of low-valent titanocene complex Cp2Ti[P(OEt)3]2 and alkylidenated Merrifield resin-bound esters to give enol ethers. Treatment of the resin-bound enol ethers with a 5:5:90 mixture of TFA, TFAA, and dichloromethane led to cleavage from resin, removal of the tert- butyldimethylsilyl (TBDMS) protecting group, and concomitant cyclization to complete the traceless solid-phase synthesis (SPS) of benzothiophenes. Switching the nature of the linker from acid-stable to acid-sensitive ensured good purity.