765302-46-3

Basic information

• Product Name: ethyl (3-methoxy-4-{[(trifluoromethyl)sulfonyl]oxy}phenyl)acetate
• Synonyms: ethyl (3-methoxy-4-{[(trifluoromethyl)sulfonyl]oxy}phenyl)acetate
• CAS NO: 765302-46-3
• Molecular Weight: 342.293
• Mol File: 765302-46-3.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: ethyl (3-methoxy-4-{[(trifluoromethyl)sulfonyl]oxy}phenyl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl (3-methoxy-4-{[(trifluoromethyl)sulfonyl]oxy}phenyl)acetate(765302-46-3)
• EPA Substance Registry System: ethyl (3-methoxy-4-{[(trifluoromethyl)sulfonyl]oxy}phenyl)acetate(765302-46-3)

Safety Data

• Hazardous Substances Data: 765302-46-3(Hazardous Substances Data)

Upstream product

• 358-23-6 trifluoromethylsulfonic anhydride 
• 60563-13-5 ethyl homovanillate 

Downstream Products

• 1255207-22-7 2-methoxy-4-(1-oxopropan-2-yl)benzonitrile 
• 1255207-24-9 4-(1-hydroxypropan-2-yl)-2-methoxybenzonitrile 
• 1255207-23-8 ethyl 2-(4-cyano-3-methoxyphenyl)propanoate 
• 1255207-16-9 ethyl (4-cyano-3-methoxyphenyl)acetate 
• 765302-47-4 ethyl 2-(3-methoxy-4-methylphenyl)acetate 
• 1428477-84-2 2-methoxy-4-[2-oxo-2-(4-{[(1-oxo-1,3-dihydro-2-benzofuran-5-yl)oxy]methyl}piperidin-1-yl)ethyl]benzonitrile 
• 1261475-10-8 (4-cyano-3-methoxyphenyl) acetic acid 

Relevant articles and documents

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

no abstract published

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kirl.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and conditions associated with excessive salt and water retention.

INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL

This invention relates to compounds having structural Formula I: and pharmaceutically acceptable salts thereof which are inhibitors of the Renal Outer Medullary Potassium (ROMK) channel (Kir1.1). The compounds of Formula I are useful as diuretics and natriuretics and therefore are useful for the therapy and prophylaxis of disorders resulting from excessive salt and water retention, including cardiovascular diseases such as hypertension and chronic and acute heart failure