765316-79-8Relevant academic research and scientific papers
Utilization of aromatic denitrocyclization reaction for the synthesis of 3-unsubstituted 1,4-dihydroquinolin-4-one derivatives
Radl, Stanislav,Obadalova, Iva
, p. 822 - 832 (2004)
Synthesis of 3-unsubstituted 1-alkyl- and 1-aryl-1,4-dihydroquinolin-4-ones from 2-nitroacetophenone via the corresponding 3-amino-1-(2-nitrophenyl)prop-2- en-1-ones and -but-2-en-1-ones by denitrocyclization reaction is described. The nucleophilic cyclization was achieved either by sodium hydride or potassium carbonate in DMF.
