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5-Methylthien-2-yl isocyanate 97% is an organic compound characterized by the presence of a methyl group attached to a thiophene ring and an isocyanate functional group. This chemical is known for its reactivity and is commonly used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals.

76536-99-7

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76536-99-7 Usage

Uses

Used in Pharmaceutical Industry:
5-Methylthien-2-yl isocyanate 97% is used as a key intermediate in the synthesis of p38 kinase inhibitors for the treatment of inflammatory diseases and certain types of cancer. Its unique structure allows for the development of potent and selective inhibitors that can modulate the activity of p38 kinase, a crucial enzyme involved in cellular signaling pathways.
Used in Agrochemical Industry:
5-Methylthien-2-yl isocyanate 97% is also utilized in the preparation of agrochemicals, specifically as a building block for the development of novel pesticides and herbicides. Its reactivity and structural features enable the creation of effective compounds that can target and control pests and weeds in agricultural settings.

Check Digit Verification of cas no

The CAS Registry Mumber 76536-99-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 7,6,5,3 and 6 respectively; the second part has 2 digits, 9 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 76536-99:
(7*7)+(6*6)+(5*5)+(4*3)+(3*6)+(2*9)+(1*9)=167
167 % 10 = 7
So 76536-99-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H5NOS/c1-5-2-3-6(9-5)7-4-8/h2-3H,1H3

76536-99-7SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-isocyanato-5-methylthiophene

1.2 Other means of identification

Product number -
Other names Thiophene,2-isocyanato-5-methyl

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:76536-99-7 SDS

76536-99-7Downstream Products

76536-99-7Relevant academic research and scientific papers

INHIBITION OF P38 KINASE ACTIVITY USING SUBSTITUTED HETEROCYCLIC UREAS

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Page/Page column 28, (2012/03/10)

This invention relates to the use of a group of aryl ureas in treating cytokine mediated diseases, other than cancer and proteolytic enzyme mediated diseases, other than cancer, and pharmaceutical compositions for use in such therapy.

INHIBITION OF RAF KINASE USING SUBSTITUTED HETEROCYCLIC UREAS

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Page/Page column 28, (2010/11/28)

Methods of treating tumors mediated by raf kinase, with substituted urea compounds, and such compounds per se.

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