76548-11-3Relevant academic research and scientific papers
Total syntheses of heliotridane and pseudoheliotridane through nitrodiene–acrylate 6π-electrocyclization/[3+2] cycloaddition
Koc, Esra,Kwon, Ohyun
, p. 4195 - 4200 (2017)
The total syntheses of the pyrrolizidine alkaloids heliotridane and pseudoheliotridane have been accomplished in six steps (overall yields: 24 and 7%, respectively) using, for the first time, the tandem 6π-electrocyclization/[3+2] dipolar cycloaddition of
Hydrogenation of pyrrolizin-3-ones; New routes to pyrrolizidines
Despinoy, Xavier L. M.,McNab, Hamish
experimental part, p. 4502 - 4511 (2009/12/25)
Pyrrolizin-3-ones (e.g.1) can be easily hydrogenated to their hexahydro (pyrrolizidin-3-one) derivatives in the presence of heterogeneous catalysts. Good diastereoselectivity (up to >97:3, depending on catalysts and solvent) can be achieved if the pyrroli
Synthesis of (±)-pseudoheliotridane by allylboration of 1-pyrroline
Gurskii,Potapova,Bubnov
, p. 1410 - 1412 (2007/10/03)
Reaction of tricrotylborane with 1-pyrroline proceeds stereoselectively to give (1R*, 1′S*)-2-(1-methylallyl)pyrrolidine. The latter was converted to the pyrrolizidine alkaloid (±)-pseudoheliotridane through hydroboration - oxidation - intramolecular cycl
