76561-84-7

Upstream product

• 193141-87-6 (3aS,4R,5S,9bR)-2,2-dimethyl-3a,4,5,9b-tetrahydronaphtho<1,2-d>dioxole-4,5-diol 
• 35185-96-7 1,2,3,4-tetrahydro-1,4-epoxynaphthalene 
• 623149-58-6 (Z)-(1R,2S,3S,4R)-Cyclodec-7-ene-5,9-diyne-1,2,3,4-tetraol 
• 222309-45-7 2,2-dimethyl-3a,9b-dihydro-naphtho[1,2-d][1,3]dioxole 
• 622785-64-2 (3aS,4R,5R,9bR)-3a,4,5,9b-tetrahydro-2,2-dimethylnaphtho[1,2-d]-1,3-dioxole-4,5-diol 
• 51268-88-3 (1R,2S)-1,2-dihydronaphthalene-1,2-diol 
• 177981-67-8 C₁₃H₁₄O₃ 
• 58717-74-1 rac-anti-naphthalene 1,2:3,4-dioxide 
• 5824-47-5 1,4-Naphthaquinone-2,3-oxide 

Relevant academic research and scientific papers

Synthesis of conduritol, conduramine, and validoxylamine analogs from tetrahydronaphthalene-cis-diol

A range of polycyclic analogs of conduritols and conduramines was prepared concisely, starting from cis-(1R,2S)-1,2-dihydronaphthalenediol. This methodology could be extended to the syntheses of validoxylamine A analogs.

Tetrahydroxy 10-Membered Cyclic Enediynes

The preparation of cyclic 10-membered tetrahydroxy enediynes is reported. The synthesis starts from tartaric acid and allows the control of the relative stereochemistry. Acetal protection of the 2,3-hydroxy groups stabilizes the enediyne during synthesis.

Synthesis and biological effects evaluation of benzoconduritols C and D from oxabenzonorbornadiene

The effective synthesis of benzoconduritols C and D is reported. Oxidation of oxabenzonorbornadiene followed by acetylation with Ac2O/pyridine or AcCl/CH2Cl2 gave the corresponding exo-diacetate compound stereoselectively.

1,2,3,4-TETRAHYDRONAPHTHALENE-1,2,3,4-TETROL COMPOUND AND METHOD FOR PRODUCING THE SAME

PROBLEM TO BE SOLVED: To provide a completely new polyol compound in the production of a polyester resin, a polyurethane resin, a polycarbonate resin or the like. SOLUTION: There is provided a 1,2,3,4-Tetrahydronaphthalene-1,2,3,4-tetrol compound represented by the formula (1). (X and Y each independently represents an alkyl group having 1 to 5 carbon atoms, an alkoxy group having 1 to 5 carbon atoms, an alkylthio group having 1 to 10 carbon atoms, a monoalkylamino group having an alkyl group having 1 to 8 carbon atoms or a dialkylamino group or a halogen atom; X and Y may be bonded to each other to form a saturated or unsaturated ring; Z represents H, a hydroxyl group, an alkyl group having 1 to 5 carbon atoms or a halogen atom.) SELECTED DRAWING: None COPYRIGHT: (C)2018,JPOandINPIT

Chemoenzymatic synthesis of conduritol analogues

Several conduritol and conduramine analogues have been synthesized from β-substituted naphthalenes via a chemoenzymatic approach, in a high regio- and stereocontrolled way. Several conduritol and conduramine analogues have been synthesized from β-substituted naphthalenes via a chemoenzymatic approach, in a high regio- and stereocontrolled way.

Enantiopure arene dioxides: Chemoenzymatic synthesis and application in the production of trans-3,4-dihydrodiols

Enantiopure syn- and anti-arene dioxides are synthesised from cis-dihydrodiol metabolites; anti-benzene dioxides are reduced to enantiopure trans-3,4-dihydrodiols while synbenzene dioxides racemise thermally via 1,4-dioxocins.

Synthesis and biological evaluation of conduritol and conduramine analogs

A number of dimeric conduritol and conduramine analogs have been synthesized from naphthalene via a combination of enzymatic and chemical methods to give oxygenated derivatives with high stereo- and regiocontrol in few steps. These compounds have been tested for enzymatic inhibition against common glycosidases.

Chemistry of anti- and syn-1,2:3,4-Naphthalene Dioxides and Their Potential Relevance as Metabolic Intermediates

The reactivity, site of attack, and stereochemistry of reactions of a variety of nucleophiles with the anti- and syn-1,2:3,4-naphthalene dioxides have been explored.In most cases, substituted tetrahydronaphthalene products arising through attack at the C-1 and C-4 positions in the anti mode were obtained.These isomeric dioxides provide excellent precursors for a number of difficultly accessible 1,4-disubstituted naphthalene derivatives such as 1,4-diphenoxynaphthalene and 1,4-dicyanonaphthalene.Evidence is also presented that anti-naphthalene dioxide constitutes an intermediate metabolite in the rat.