76572-70-8

Usage

InChI:InChI=1/C10H13N3OS/c1-2-11-10(15)13-12-7-8-5-3-4-6-9(8)14/h3-7,12H,2H2,1H3,(H2,11,13,15)/b8-7+

Upstream product

• 13431-34-0 N-ethylthiosemicarbazide 
• 89-95-2 2-methyl-benzyl alcohol 
• 90-02-8 salicylaldehyde 

Downstream Products

• 1415313-64-2 [Ni2(κ3-O, N3, S-C10H11N3OS)2(μ-P, P-bis(diphenylphosphino)methane)] 
• 1610980-15-8 C₄₇H₄₂ClN₃O₂P₂RuS 
• 1610980-15-8 C₄₇H₄₂N₃O₂P₂RuS⁽¹⁺⁾*Cl^(1-) 
• 61872-10-4 C₁₀H₁₁N₃OS^(2-)*Cu⁽²⁺⁾ 

Relevant academic research and scientific papers

Impact and correlation of p: K a and dn electrons of some selected thiosemicarbazone Schiff base metal Co, Ni, Cu complexes: A study of electrochemical behavior, excitation and optical energies

The electron-transfer and coordination mechanism of Schiff bases with metal ions, correlation of the electrochemical and optical properties for their potential applications in various fields of chemistry and biochemistry are underexplored. Thus, detailed

Electronic Fine-Tuning of Oxygen Atom Transfer Reactivity of cis-Dioxomolybdenum(VI) Complexes with Thiosemicarbazone Ligands

A series of six cis-dioxomolybdenum(VI) complexes with thiosemicarbazone ligands was synthesized and characterized. The ligands were obtained by reacting ethyl thiosemicarbazide with salicylaldehydes substituted with a selection of electron-withdrawing an

DNA binding, antioxidant, cytotoxicity (MTT, lactate dehydrogenase, NO), and cellular uptake studies of structurally different nickel(II) thiosemicarbazone complexes: Synthesis, spectroscopy, electrochemistry, and X-ray crystallography

Three new nickel(II) thiosemicarbazone complexes have been synthesized and characterized by analytical, spectral, and single-crystal X-ray diffraction studies. In complex 1, the ligand 2-hydroxy-1-naphthaldehydethiosemicarbazone coordinated as a monobasic tridentate donor, whereas in complexes 2 and 3, the ligands salicylaldehyde-4(N)-ethylthiosemicarbazone and 2-hydroxy-1- naphthaldehyde-4(N)-ethylthiosemicarbazone coordinated as a dibasic tridentate donor. The DNA binding ability of the complexes in calf thymus DNA was explored by absorption and emission titration experiments. The antioxidant property of the new complexes was evaluated to test their free-radical scavenging ability. In vitro cytotoxicity assays were performed for the new complexes in A549 and HepG2 cell lines. The new compounds overcome cisplatin resistance in the A549 cell line and they were also active in the HepG2 cell line. The cellular uptake study showed the accumulation of the complexes in tumor cells depended on the nature of the ligand attached to the nickel ion. Graphical abstract: Structurally different nickel(II) thiosemicarbazone complexes for which DNA binding, antioxidant, cytotoxicity, and cellular uptake studies were performed [Figure not available: see fulltext.]

Spectroscopic, thermal and electrochemical studies on some nickel(II) thiosemicarbazone complexes

Several complexes of thiosemicarbazone derivatives with Ni(II) have been prepared. Structural investigation of the ligands and their complexes has been made based on elemental analysis, magnetic moment, spectral (UV-Vis, i.r., 1H NMR, ms), and