76578-14-8

Basic information

• Product Name: Quizalofop-ethyl
• Synonyms: All-in-one;Assure (Du Pont);Assure Ⅱ (Du Pont);Pilot (Schering AG);pilot Super (Schering AG);Targa.Targa Dt(Rh one-Poulenc),Targa Super;QUIZALOFOP ETHYL, 100MG, NEAT;QUIZALOFOP-ETHYL PESTANAL, 50 MG
• CAS NO: 76578-14-8
• Molecular Formula: C₁₉H₁₇ClN₂O₄
• Molecular Weight: 372.8
• Mol File: 76578-14-8.mol
• Article Data: 7

Chemical Properties

• Melting Point: 92-93°
• Boiling Point: bp0.2 220°
• Flash Point: 100 °C
• Appearance: /
• Density: 1.2671 (rough estimate)
• Vapor Pressure: 3.05E-10mmHg at 25°C
• Refractive Index: 1.6800 (estimate)
• Storage Temp.: 0-6°C
• PKA: -1.39±0.48(Predicted)
• Water Solubility: 303ug/L(temperature not stated)
• Merck: 13,8178
• BRN: 7145610
• CAS DataBase Reference: Quizalofop-ethyl(CAS DataBase Reference)
• NIST Chemistry Reference: Quizalofop-ethyl(76578-14-8)
• EPA Substance Registry System: Quizalofop-ethyl(76578-14-8)

Safety Data

• Hazard Codes: Xn
• Statements: 21/22
• Safety Statements: 22-24/25
• RIDADR: UN3077 9/PG 3
• WGK Germany: 3
• RTECS: UA2458255
• Hazardous Substances Data: 76578-14-8(Hazardous Substances Data)

Usage

Chemical Properties

White crystalline solid or powder. Commercial product is available as an emulsifiable con- centrate. Practically insoluble in water; solubili- ty≤2×10-28 ppm.

Uses

Different sources of media describe the Uses of 76578-14-8 differently. You can refer to the following data:
1. Herbicide.
2. Quizalofop-ethyl is a selective postemergence herbicide used to control both annual and perennial grasses in soybeans and cotton.

General Description

White crystals. Insoluble in water. Used as an herbicide.

Air & Water Reactions

Insoluble in water.

Reactivity Profile

A halogenated ester and amine. Amines are chemical bases. They neutralize acids to form salts plus water. These acid-base reactions are exothermic. The amount of heat that is evolved per mole of amine in a neutralization is largely independent of the strength of the amine as a base. Amines may be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated by amines in combination with strong reducing agents, such as hydrides. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Agricultural Uses

Herbicide: Not approved for use in EU countries. Registered for use in the U.S.

Trade name

ASSURE?[C]; DPX-Y 6202?; FBC?; 32197; INY-6202; MATADOR?; LEOPARD EC (p-isomer); MON? 78746; NC-302?; PILOT?; SUPER MATADOR (p-isomer); TARGA?; ULTRA TARGA (p-isomer)

Potential Exposure

A chlorophenoxy/aryloxyphenoxypro- pionate herbicide

Environmental Fate

Plant. Rapidly hydrolyzed in plants to quizalofop and ethanol (Humburg et al., 1989).

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous haz- ardous material, Technical Name Required.

Waste Disposal

It is the responsibility of chem- ical waste generators to determine the toxicity and physical properties and of a discarded chemical and to properly iden- tify its classification and certification as a hazardous waste and to determine the disposal method. United States Environmental Protection Agency guidelines for the classifi- cation determination are listed in 40 CFR Parts 261.3. In addi- tion, waste generators must consult and follow all regional, national, state, and local hazardous waste laws to ensure com- plete and accurate classification and disposal methods.

InChI:InChI=1/C19H17ClN2O4/c1-3-24-19(23)12(2)25-14-5-4-6-15(10-14)26-18-11-21-17-9-13(20)7-8-16(17)22-18/h4-12H,3H2,1-2H3

Upstream product

• 74497-15-7 (L) Ethyl 2-chloropropanoate 
• 76578-79-5 6-chloro-2-(4-hydroxyphenoxy)quinoxaline 
• 687-47-8 (S)-Ethyl lactate 
• 18671-97-1 2,6-dichloroquinoxaline 
• 64-17-5 ethanol 
• 94050-90-5 (R)-2-(4-hydroxyphenoxy)propionic acid 
• 57057-80-4 ethyl (S)-2-[[(4-methylphenyl)sulfonyl]oxy]propanoate 

Downstream Products

• 200509-41-7 (RS)-tetrahydrofuran-2-ylmethyl (R)-2-[4-(6-chloro-2-quinoxalinyloxy)phenoxy]propionate 
• 94051-08-8 quizalofop-p 

Relevant articles and documents

Synthesis method of quizalofop-P (by machine translation)

The invention belongs to the field of chemical engineering, and particularly relates to a synthetic method of quizalofop-methyl. To the invention, ethyl S-2 - ethyl chloropropionate is used instead S-2 - benzene sulfonic acid ethyl propionate, the esterification reaction step is omitted, the harsh reaction conditions and tedious post-treatment process are avoided, and meanwhile benzene sulfonate introduced by S-2 - benzenesulfonic acid ethyl propionate is avoided, and the environmental protection benefit of the process is improved. (by machine translation)

A Direct Approach to Enantiopure Propionate Derivatives from Ethyl Lactate

The S-propargyl xanthate derived from ethyl (S)-lactate reacts upon heating with various acidic substances to give the propionate transfer product in high yield and with complete inversion of configuration.

A new method for one-pot synthesis of aryloxyphenoxypropionate herbicides using 2,4,6-trichloro-1,3,5-triazine and (n-BU)4NI as a homogeneous catalyst

The one-pot reaction of halo-heterocycle, (R)-4-hydroxyphenoxy propionic acid and an alcohol, amine or sulfonamide is described as an efficient method for the synthesis of aryloxyphenoxy propionate hrerbicides by using 2,4,6-trichloro-1,3,5-triazine in the presence of (n-BU) 4NI, as a homogeneous catalyst under mild conditions. The present procedure offers several advantages, such as good yields, short reaction times and easy workup.