76591-84-9

Upstream product

• 587-04-2 m-Chlorobenzaldehyde 
• 76226-60-3 (3-chlorophenyl)-morpholino-methanethione 
• 74-88-4 methyl iodide 

Downstream Products

• 111997-57-0 2-(3-chlorophenyl)-5-(pyridin-4-yl)-1,3,4-oxadiazole 
• 76226-78-3 N-[1-(3-Chloro-phenyl)-1-morpholin-4-yl-meth-(Z)-ylidene]-N'-quinolin-2-yl-hydrazine; hydriodide 
• 79442-06-1 phenyl-2 (chloro-3 phenyl)-5 oxadiazole-1,3,4 
• 111997-56-9 2-[5-(3-Chloro-phenyl)-[1,3,4]oxadiazol-2-yl]-phenol 
• 76591-82-7 2-[5-(3-Chloro-phenyl)-4H-[1,2,4]triazol-3-yl]-pyridine 
• 111997-48-9 2-(m-Chloro-α-morpholinobenzylidene)salicylohydrazide 

Relevant academic research and scientific papers

Studies on Thioamides and Their Derivatives,VI. New Synthesis of 5-Membered Heterocyclic Compounds

Simple N-monosubstituted thioamides react with acid hydrazides to form 1,2,4-triazole derivatives.N,N-Disubstituted thioamides alkylated with methyl iodide readily yield with acid hydrazides 1,3,4-oxadiazoles.

STUDIES ON THIOAMIDES AND THEIR DERIVATIVES. PART II. REACTION OF QUATERNARY SALTS OF N,N-DISUBSTITUTED THIOAMIDES WITH 2-HYDRAZINOQUINOLINE

In reactions of methyliodides of N,N-disubstituted thioamides with 2-hydrazinoquinoline a series of new compounds have been obtained: iodohydrides, derivatives of 1-α-morpholinobenzylidene-2-quinolinohydrazine and of 1-α-piperidinobenzylidene-2-quinolinohydrazine.The compounds obtained, when transformed into free bases, undergo cyclization to derivatives of s-triazolo(4,3-a)quinoline system under the effect of glacial acetic acid.All these compounds have been characterized by means of UV and IR spectra.