765915-16-0Relevant academic research and scientific papers
Iterative deoxypropionate synthesis based on a copper-mediated directed allylic substitution
Breit, Bernhard,Herber, Christian
, p. 3790 - 3792 (2007/10/03)
Can't have too much of a good thing: A flexible, iterative strategy based on a highly selective copper-mediated allylic substitution makes the preparation of any desired oligo(deoxypropionate) stereoisomer possible (see scheme; RDG = reagent-directing group). This approach differs from the established enolate-alkylation methodology through the reversed polarity of the reaction partners and avoids several problems associated with the latter method.
