765936-44-5

Upstream product

• 579494-03-4 6-O-allyl-3,4,5-tri-O-benzyl-1-O-(4-methoxybenzyl)-2-O-(3,4,6-tri-O-benzyl-α-D-mannopyranosyl)-(1->2)-L-myo-inositol 
• 579494-04-5 6-O-allyl-3,4,5-tri-O-benzyl-1-O-(4-methoxybenzyl)-2-O-(2,3,4,6-tetra-O-benzyl-α-D-mannopyranosyl)-(1->2)-L-myo-inositol 

Relevant academic research and scientific papers

Synthesis of serine-linked phosphatidylinositol mannosides (PIMs)

The 6-O-allyl group of inositol mannoside (D)-6 was used for the generation of O-linked serine residues via a sequence of dihydroxylation, selective 3″-O-protection, introduction of the 2″-amino group, deprotection, and oxidation of the 3″-position. Attachment of the phosphatidyl residue to 1-O of the inositol moiety and complete deprotection furnished target molecules (D)-1 and (D)-2. Alternatively, instead of introduction of a 6-O-allyl group, 2″,3″-dihydroxy propanylation of the 6-O-position of the inositol moiety using a silyl-protected cyclic sulfate of glycerol was possible. Thus, target molecule (L)-3 was obtained. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2004.