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Usage

Uses

Used in Organic Synthesis:
3-[5-(3-NITRO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID is used as a reagent in organic synthesis for its ability to participate in various reactions such as Michael addition and Diels-Alder reactions, facilitating the creation of complex organic molecules.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 3-[5-(3-NITRO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID is used as a building block for the synthesis of complex organic molecules with specific properties, potentially leading to the development of new drugs.
Used in Agrochemical Industry:
3-[5-(3-NITRO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID is utilized in the agrochemical industry for the synthesis of compounds with pesticidal properties, contributing to the development of effective crop protection agents.
Used in Material Science:
3-[5-(3-NITRO-PHENYL)-FURAN-2-YL]-ACRYLIC ACID is used in material science for its potential to contribute to the development of new materials with unique properties, such as improved stability or reactivity.

Upstream product

• 13148-43-1 5-(3-nitrophenyl)furfural 
• 141-82-2 malonic acid 
• 13331-27-6 m-nitrobenzene boronic acid 
• 938056-34-9 methyl (E)-3-[5-(3-nitrophenyl)-furan-2-yl]acrylate 

Relevant academic research and scientific papers

Development of molecular probes for second-site screening and design of protein tyrosine phosphatase inhibitors

We report on the design, synthesis, and evaluation of a series of furanyl-salicyl-nitroxide derivatives as effective chemical probes for second-site screening against phosphotyrosine phosphatases (PTPs) using NMR-based techniques. The compounds have been

Non-thiol farnesyltransferase inhibitors: N-(4-tolylacetylamino-3- benzoylphenyl)-3-arylfurylacrylic acid amides

We have designed arylfurylacryl-substituted benzophenones as non-thiol farnesyltransferase inhibitors utilizing a novel aryl binding site of farnesyltransferase. These compounds display activity in the low nanomolar range. We have designed arylfurylacryl-

Structure-activity relationships of novel anti-malarial agents. Part 4: N-(3-Benzoyl-4-tolylacetylaminophenyl)-3-(5-aryl-2-furyl)acrylic acid amides

In a previous report, we have described novel anti-malarial compounds based on a 2,5-diaminobenzophenone scaffold. Here, we have invesigated acryloyl derivatives carrying a biaryl structure consisting of a terminal aryl residue and a central 2-furyl ring. Several compounds were obtained in the series of para-substituted phenylfurylacryloyl derivatives that displayed improved anti-malarial activity in comparison to earlier described derivatives. From the structure-activity relationships it can be deduced that there has to be a lipophilic moiety in the para-position of the terminal phenyl residue. Furthermore, there are indications that, alternatively, activity may benefit from the presence of a polar moiety with hydrogen bond acceptor properties.