76606-68-3

Basic information

• Product Name: 2-(3,4-DICHLORO-PHENYL)-5-METHYL-2H-PYRAZOL-3-YLAMINE
• Synonyms: 2-(3,4-dichlorophenyl)-5-methylpyrazol-3-amine
• CAS NO: 76606-68-3
• Molecular Formula: C₁₀H₉Cl₂N₃
• Molecular Weight: 242.1
• Mol File: 76606-68-3.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 396.5°C at 760 mmHg
• Flash Point: 193.6°C
• Appearance: /
• Density: 1.45g/cm³
• Vapor Pressure: 1.7E-06mmHg at 25°C
• Refractive Index: 1.659
• CAS DataBase Reference: 2-(3,4-DICHLORO-PHENYL)-5-METHYL-2H-PYRAZOL-3-YLAMINE(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-DICHLORO-PHENYL)-5-METHYL-2H-PYRAZOL-3-YLAMINE(76606-68-3)
• EPA Substance Registry System: 2-(3,4-DICHLORO-PHENYL)-5-METHYL-2H-PYRAZOL-3-YLAMINE(76606-68-3)

Safety Data

• Hazardous Substances Data: 76606-68-3(Hazardous Substances Data)

Usage

Chemical Class

Pyrazole derivatives

Structural Feature

Pyrazole ring substituted with a 3,4-dichlorophenyl group and a methyl group

Potential Applications

Pharmaceutical industry

Biological Activity

Inhibitor of specific enzymes

Preclinical Research

Promise for treatment of certain diseases

Importance

Building block for synthesis of novel pharmaceuticals and bioactive compounds, valuable asset in medicinal chemistry.

InChI:InChI=1/C10H9Cl2N3/c1-6-4-10(13)15(14-6)7-2-3-8(11)9(12)5-7/h2-5H,13H2,1H3

Upstream product

• 1118-61-2 3-Aminocrotononitrile 
• 19763-90-7 3,4-dichlorophenylhydrazine hydrochloride 

Downstream Products

• 76606-69-4 1-acetyl-2-[2-(3,4-dichloro-phenyl)-5-methyl-2H-pyrazol-3-ylamino]-4,5-dihydro-1H-imidazole 
• 120163-42-0 5-(3,4-Dichloro-phenyl)-7-methyl-5H-pyrazolo[4,3-c][1,2,5]oxadiazin-3-one 
• 442850-77-3 N-[2-(3,4-dichloro-phenyl)-5-methyl-2H-pyrazol-3-yl]-2,2,2-trifluoro-thioacetamide 
• 442850-67-1 N-[2-(3,4-dichloro-phenyl)-5-methyl-2H-pyrazol-3-yl]-2,2,2-trifluoro-acetamide 
• 120163-40-8 5-amino-1-(3,4-dichlorophenyl)-3-methyl-4-nitrosopyrazole 

Relevant articles and documents

Amidinosemicarbazido derivatives of pyrazole: Synthesis and inhibitory effect on blood coagulation and platelet aggregation

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Pyrazolyl amino imidazolines as antihypertensive agents

Described is a method of treating hypertensive by administering to mammalian patients compounds of the formula STR1 wherein R1 and R2 are hydrogen, loweralkyl, lowercycloalkyl, aralkyl, aryl, pyridyl, isoquinolyl, phthalazinyl, or aryl substituted by one or more hydrogen, halo, loweralkyl, lowercycloalkyl, haloloweralkyl, haloloweralkyl, aminosulfonyl, nitro, hydroxy, alkoxy, carboxy, alkoxycarbonyl, cycloalkoxy carbonyl, aminocarbonyl, diloweralkylaminocarbonyl or STR2 wherein n is 4 or 5. R3 is hydrogen, halogen, loweralkyl or aryl, and R4 is hydrogen, acyl, amino or loweralkyl, and the pharmaceutically acceptable acid addition salts thereof.