766498-73-1 Usage
General Description
"(1S)-1-(4-chlorophenyl)-2,2,2-trifluoroethylamine" is a chemical compound with the molecular formula C8H8ClF3N. It is a chiral compound, with the S enantiomer being the active form. (1S)-1-(4-CHLOROPHENYL)-2,2,2-TRIFLUOROETHYLAMINE is commonly used as an intermediate or starting material in the production of various pharmaceuticals, agrochemicals, and other fine chemicals. It may also be used as a reagent in organic synthesis, particularly in the formation of carbon-carbon and carbon-heteroatom bonds. Additionally, it has been studied for its potential use in the development of novel drug candidates and as a building block for creating diverse chemical libraries for drug discovery.
Check Digit Verification of cas no
The CAS Registry Mumber 766498-73-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 7,6,6,4,9 and 8 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 766498-73:
(8*7)+(7*6)+(6*6)+(5*4)+(4*9)+(3*8)+(2*7)+(1*3)=231
231 % 10 = 1
So 766498-73-1 is a valid CAS Registry Number.
InChI:InChI=1/C8H7ClF3N/c9-6-3-1-5(2-4-6)7(13)8(10,11)12/h1-4,7H,13H2/t7-/m0/s1
766498-73-1Relevant articles and documents
Silver-catalyzed formal [3+2]-cycloaddition of α-trifluoromethylated methyl isocyanides: a facile stereoselective synthesis of CF3-substituted heterocycles
Zhang, Xue,Wang, Xin,Gao, Yuelei,Xu, Xianxiu
supporting information, p. 2427 - 2430 (2017/03/01)
An Ag-catalyzed formal [3+2]-cycloaddition of α-trifluoromethylated methyl isocyanides with polar double bonds has been developed for the facile access to trifluoromethylated oxazolines, imidazolines and pyrrolines under mild conditions. The practicality of this chemistry is demonstrated by the gram-scale synthesis of oxazolines with excellent yields and facile transformations of the formed oxazolines to trifluoromethylated β-amino alcohols in quantitative yields.
Aryltrifluoroethylamines
-
, (2008/06/13)
Certain arylmethyl amines have been prepared wherein the "methyl" carbon is substituted with a polyfluoroalkyl radical. The compounds form acid addition salts, exist in resolvable stereoisomeric forms, and are useful for treating hypertension. Formulations for human and veterinary medicine are described, as well as methods of use.
