766527-51-9Relevant academic research and scientific papers
Structural characterization of O- and C-glycosylating variants of the landomycin glycosyltransferase LanGT2
Tam, Heng Keat,H?rle, Johannes,Gerhardt, Stefan,Rohr, Jürgen,Wang, Guojun,Thorson, Jon S.,Bigot, Aurlien,Lutterbeck, Monika,Seiche, Wolfgang,Breit, Bernhard,Bechthold, Andreas,Einsle, Oliver
supporting information, p. 2811 - 2815 (2015/03/04)
The structures of the O-glycosyltransferase LanGT2 and the engineered, C-C bond-forming variant LanGT2S8Ac show how the replacement of a single loop can change the functionality of the enzyme. Crystal structures of the enzymes in complex with a nonhydroly
Enantioselective synthesis of 2,6-dideoxy carbasugars based on a desymmetrizing hydroformylation-carbonyl ene cyclization process
Breit, Bernhard,Bigot, Aurelien
, p. 6498 - 6500 (2009/04/13)
A practical one-pot process involving a desymmetrizing hydroformylation with the aid of a chiral catalyst-directing group (CDG*), followed by a carbonyl ene cyclization provides a straightforward access to both enantiomers of the resulting cyclohexanediol; further divergent, highly selective and protecting group-free transformations furnish the carbocyclic analogues of four important 2,6-dideoxysugars. The Royal Society of Chemistry 2008.
Desymmetrizing hydroformylation with the aid of a planar chiral catalyst-directing group
Breit, Bernhard,Breuninger, Daniel
, p. 10244 - 10245 (2007/10/03)
Desymmetrizing hydroformylation of bisalkenyl- and bisallylcarbinols could be achieved employing a chiral substrate-bound catalyst-directing group (o-DPPF) with excellent levels of diastereotopic alkene face and diastereotopic alkene group discrimination to give bifunctionalized chiral aldehydes in enantiomerically pure form. Copyright
