766545-64-6Relevant academic research and scientific papers
Evidence for separate binding and scaffolding domains in the immunosuppressive and antitumor marine natural product, pateamine A: Design, synthesis, and activity studies leading to a potent simplified derivative
Romo, Daniel,Choi, Nam Song,Li, Shukun,Buchler, Ingrid,Shi, Zonggao,Liu, Jun O.
, p. 10582 - 10588 (2004)
Pateamine A (PatA), a marine metabolite from Mycale sp., is a potent inhibitor of the intracellular signal transduction pathway emanating from the T-cell receptor leading to the transcription of cytokines such as interleukin-2 (IL-2). On the basis of the
