766549-85-3

Upstream product

• 90283-59-3 p-toluic acid N-(1,2,2-trichloroethyl)amide 
• 766549-83-1 N-(2-chloro-1-cyano-vinyl)-4-methyl-benzamide 

Relevant academic research and scientific papers

2-Acylamino-3-chloroacrylonitriles, promising reagents for heterocyclization

2-Acylamino-3-chloroacrylonitriles prepared by treating available N-(1,2,2-trichloroethyl)amides of carboxylic acids with sodium cyanide readily undergo cyclization in the presence of excess hydrazine hydrate. The cyclization products, 5-amino-4-acylaminopyrazoles, were applied to the synthesis of new imidazo[4,5-c]pyrazole and pyrazolo[1,5-a]pyrimidine derivatives.