76700-02-2

Basic information

• Product Name: 2-(p-Chloro-benzoyl)-hydrazino-4,5,6,7-tetrahydrobenzothiazole
• CAS NO: 76700-02-2
• Molecular Weight: 307.804
• Mol File: 76700-02-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-(p-Chloro-benzoyl)-hydrazino-4,5,6,7-tetrahydrobenzothiazole(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(p-Chloro-benzoyl)-hydrazino-4,5,6,7-tetrahydrobenzothiazole(76700-02-2)
• EPA Substance Registry System: 2-(p-Chloro-benzoyl)-hydrazino-4,5,6,7-tetrahydrobenzothiazole(76700-02-2)

Safety Data

• Hazardous Substances Data: 76700-02-2(Hazardous Substances Data)

Upstream product

• 64310-32-3 1-(4-chlorobenzoyl)thiosemicarbazide 
• 822-87-7 2-Chlorocyclohexanone 
• 536-40-3 4-chlorobenzoic acid hydrazide 
• 1126-46-1 Methyl 4-chlorobenzoate 

Relevant articles and documents

Condensed Tetrahydrobenzothiazoles: Part II- Synthesis of 2-Aryl-5,6,7,8-tetrahydro-s-triazolobenzothiazoles and 3-Aryl-5,6,7,8-tetrahydro-s-triazolobenzothiazoles

Cyclization of 1-aroylthiosemicarbazides (I) under alkaline conditions gives 3-mercapto-5-aryl-s-triazoles (II), while their condensation with 2-chlorocyclohexanone (IIIa) furnishes 2-aroylhydrazino-4,5,6,7-tetrahydrobenzothiazoles (IV).The reaction of II with IIIa affords 2-aryl-5,6,7,8-tetrahydro-s-triazolobenzothiazoles (Va).Structure of Va has been established by comparison with isomeric 3-aryl-5,6,7,8-tetrahydro-s-triazolobenzothiazoles (VI), obtained by cyclization of IV.The reaction of 2-bromo-6-carbethoxycyclohexanone (IIIb) with II does not produce the expected 5-carbethoxy-2-aryl-5,6,7,8-tetrahydro-s-triazolo benzothiazoles (Vb), but gives Va.Hydrolysis and decarboxylation of Vb during the reaction to form Va are discussed.