767342-28-9Relevant academic research and scientific papers
COMPOUNDS WHICH BIND TO THE ACTIVE SITE OF PROTEIN KINASE ENZYMES
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Page/Page column 32, (2008/06/13)
One or more compounds that are inhibitors of a serine/ threonine kinase, more particularly Rho kinase (ROK, ROCK) can be used in the manufacture of a medicament for treatment or prophylaxis of a condition selected from: an ocular condition including age r
COMPOUNDS WHICH BIND TO THE ACTIVE SITE OF PROTEIN KINASE ENZYMES
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Page 32, (2008/06/13)
The present invention relates to a compound and a group of compounds which are inhibitors of Rho kinase (ROK, ROCK). In addition, the invention relates to methods of treatment and use of the compounds in the manufacture of a medicament for application to
COMPOUND LIBRARIES
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Page 28, (2010/02/08)
The present invention relates to compounds capable of binding to the active site of protein kinase enzymes. The invention further relates to libraries of compounds and a family of libraries of compounds for use in screening programmes against protein kinases as well as the individual compounds for use in hit to lead and lead optimisation projects, and similar stages in the drug discovery process. The invention also provides methods for making compounds and libraries.
