76746-16-2

Basic information

• Product Name: 2-amino-3-methylbenzohydrazide
• Synonyms: 2-amino-3-methylbenzohydrazide
• CAS NO: 76746-16-2
• Molecular Weight: 165.195
• Mol File: 76746-16-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: 2-amino-3-methylbenzohydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-3-methylbenzohydrazide(76746-16-2)
• EPA Substance Registry System: 2-amino-3-methylbenzohydrazide(76746-16-2)

Safety Data

• Hazardous Substances Data: 76746-16-2(Hazardous Substances Data)

Upstream product

• 22223-49-0 methyl 2-amino-3-methylbenzoate 
• 4389-45-1 3-methylantranilic acid 

Downstream Products

• 1609006-93-0 ethyl 5-(2-(3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamido)-3-methylphenyl)-2,2-dimethyl-1,3,4-oxadiazole-3(2H)-carboxylate 
• 1609006-92-9 methyl 5-(2-(3-bromo-1-(3-chloropyridin-2-yl)-1H-pyrazole-5-carboxamido)-3-methylphenyl)-2,2-dimethyl-1,3,4-oxadiazole-3(2H)-carboxylate 
• 1609006-80-5 ethyl 5-(2-amino-3-methylphenyl)-2,2-dimethyl-1,3,4-oxadiazole-3(2H)-carboxylate 
• 1609006-79-2 methyl 5-(2-amino-3-methylphenyl)-2,2-dimethyl-1,3,4-oxadiazole-3(2H)-carboxylate 
• 1609006-69-0 2-amino-3-methyl-N'-(propan-2-ylidene)benzohydrazide 

Relevant articles and documents

Aryl or heteroaryl methoxylation reaction method

The invention discloses an aryl or heteroaryl methoxylation reaction method. The method comprises the following steps: preparing a substrate. The coupling agent, ligand, solvent, catalyst and base are mixed homogeneously in an inert gas to give the aryl or heteroaryl methoxy compounds. Compared with a methoxylation reaction method in the prior art, the method has the advantages that the reaction system conditions are mild, the usage amount of the catalyst and the ligand is low to 5% of the amount of the substrate material, and the catalytic efficiency is improved. The method has better compatibility to different substrate expansion and discovery of aryl halides or heteroaryl halides with different functional groups. The yield of aryl or heteroaryl methoxy compounds prepared by the method disclosed by the invention is 36% - 89%.

Synthesis of diverse azolo[c]quinazolines by palladium(II)- catalyzed aerobic oxidative insertion of isocyanides

We report the palladium(II)-catalyzed aerobic oxidative coupling of isocyanides with various (2-aminophenyl)azoles using air as the stoichiometric oxidant. A diverse range of medicinally valuable azolo[c]quinazolines was obtained by this new approach.

Pyrazoloquinazolin-9-ones: A New Series of Antiallergic Agents

A new series of antiallergic agents, pyrazoloquinazolin-9-ones, was synthesized and evaluated for inhibitory effects in the rat reaginic passive cutaneous anaphylaxis (PCA) screen.Several analogues were found to be more potent than cromolyn sodium intravenously.Structure-activity relationships are discussed.One of the compounds, 4,9-dihydro-5-methoxy-9-oxopyrazoloquinazoline-2-carboxylic acid (36), was found to be approximately 250 times more potent than cromolyn sodium intravenously.