76746-82-2Relevant academic research and scientific papers
Tagged phosphine reagents to assist reaction work-up by phase-switched scavenging using a modular flow reactor
Smith, Christopher D.,Baxendale, Ian R.,Tranmer, Geoffrey K.,Baumann, Marcus,Smith, Stephen C.,Lewthwaite, Russell A.,Ley, Steven V.
, p. 1562 - 1568 (2007)
The use of three orthogonally tagged phosphine reagents to assist chemical work-up via phase-switch scavenging in conjunction with a modular flow reactor is described. These techniques (acidic, basic and Click chemistry) are used to prepare various amides
Ultrasound-assisted synthesis of substituted guanidines from thioureas
Pattarawarapan, Mookda,Jaita, Subin,Wangngae, Sirilak,Phakhodee, Wong
supporting information, p. 1354 - 1358 (2018/03/29)
Ultrasound-assisted synthesis of guanidine derivatives was developed using 2,4,6-trichloro-1,3,5-triazine as an inexpensive dehydrosulfurization reagent. Both 1,3-alkylaryl- and 1,3-diaryl-thioureas were rapidly converted into carbodiimides before subsequent reaction with aromatic or aliphatic amines. The method allows rapid access to highly substituted guanidines in good to excellent yields under mild conditions and with minimal use of solvent.
Oxidation of Mixtures of Thioureas: Part VIII - Formation of 3-Amino-4-aryl-5-benzylimino-4,5-dihydro-1,2,4-thiadiazoles
Indukumari, P. V.,Joshua, C. P.
, p. 672 - 675 (2007/10/02)
Oxidation of binary mixtures of 1-aryl-3-benzylthioureas and thiourea in acidic ethanol affords 3-amino-4-aryl-5-benzylimino-4,5-dihydro-1,2,4-thiadiazoles (3). 1-Aryl-3-benzylthioureas used are: 1-phenyl-3-benzyl-, 1-p-tolyl-3-benzyl-, 1-benzyl-3-p-chlorophenyl-, 1-p-anisyl-3-benzyl- and 1-benzyl-3-p-nitrophenyl-thioureas.
