76746-92-4

Basic information

• Product Name: 4-carbomethoxy-7-methoxy-3-methylisoquinolone
• CAS NO: 76746-92-4
• Molecular Weight: 247.251
• Mol File: 76746-92-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-carbomethoxy-7-methoxy-3-methylisoquinolone(CAS DataBase Reference)
• NIST Chemistry Reference: 4-carbomethoxy-7-methoxy-3-methylisoquinolone(76746-92-4)
• EPA Substance Registry System: 4-carbomethoxy-7-methoxy-3-methylisoquinolone(76746-92-4)

Safety Data

• Hazardous Substances Data: 76746-92-4(Hazardous Substances Data)

Upstream product

• 25113-11-5 4-carbomethoxy-7-methoxy-3-methylisocoumarin 

Relevant articles and documents

Isoquinolones: Part IV - Synthesis of 3-Methylisoquinolone-4-carboxylic Acids and Action of Ammonia and Aqueous Methyl Amine on 3-Methylisocoumarin-4-carboxylic Acid Esters

Ammonia reacts with 3-methylisocoumarin-4-carboxylic acid ester (II) on a boiling water-bath to give homophthalimide (III, R'=H) and 3-methylisoquinolone-4-carboxylic acid ester (IV) in nearly equal amounts.At room temperature ammonia reacts to give IV as the major product in good yield.Aq. methyl amine, however, reacts with II to give N-methylhomophthalimide (III, R'=Me) as the major product along with small amounts of compound VI (R1=Me) and some unchanged isocoumarin.Formation of the various products has been rationalised.