767590-77-2Relevant academic research and scientific papers
Regioselective lipase-catalysed amidation of dicarboxylic N-blocked amino acid diesters - Effect of the side-chain length
Conde, Santiago,López-Serrano, Paloma,Castro, Ana,Martínez, Ana
, p. 2835 - 2839 (2007/10/03)
Diethyl esters of both (R)- and (S)-N-blocked α-aminoadipic and α- aminopimelic acids yield exclusively the ω-monoamide when they are subjected to amidation catalysed by the lipase B of Candida antarctica in anhydrous diisopropyl ether. These results are
Composition containing a penem or carbapenem antibiotic
-
, (2008/06/13)
Administration of an N-acylated amino acid in association with a penem or carbapenem antibiotic relieves or eliminates the renal problems associated with administration of the antibiotic alone. The amino acid derivative and antibiotic may be formulated together as a composition or administered separately, either simultaneously or sequentially. The composition may be prepared by simple mixing.
