76781-68-5

Basic information

• Product Name: ethyl 6-(4-methoxyphenyl)-4-oxo-4H-pyran-2-carboxylate
• Synonyms: ethyl 6-(4-methoxyphenyl)-4-oxo-4H-pyran-2-carboxylate
• CAS NO: 76781-68-5
• Molecular Weight: 274.273
• Mol File: 76781-68-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: ethyl 6-(4-methoxyphenyl)-4-oxo-4H-pyran-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: ethyl 6-(4-methoxyphenyl)-4-oxo-4H-pyran-2-carboxylate(76781-68-5)
• EPA Substance Registry System: ethyl 6-(4-methoxyphenyl)-4-oxo-4H-pyran-2-carboxylate(76781-68-5)

Safety Data

• Hazardous Substances Data: 76781-68-5(Hazardous Substances Data)

Upstream product

• 3001-72-7 DBN 

Downstream Products

• 76782-16-6 6-(4-Methoxyphenyl)-2-tetrazol-5-yl-4H-pyran-4-one 
• 76782-14-4 2-cyano-6-p-methoxyphenyl-4-pyrone 
• 78296-78-3 4-Chloro-6-(4-methoxy-phenyl)-pyridine-2-carboxylic acid (1H-tetrazol-5-yl)-amide 
• 76782-10-0 6-p-methoxyphenyl-4-pyrone-2-carboxamide 

Relevant articles and documents

6-Substituted pyranone compounds and their use as pharmaceuticals

Compounds are described of the formula STR1 in which R1 is COOR5, CONHR5, cyano, 5-tetrazolyl or R6, where R5 is hydrogen or C1-8 alkyl and R6 is phenyl or naphthyl, the phenyl or naphthyl group being optionally substituted by one or more group selected from halogen, C1-6 alkyl, C1-4 alkoxy, hydroxy, benzyloxy, nitro, trifluoromethyl, carboxyl, C1-4 alkylsulphinyl, C1-4 alkylsulphonyl, N(R5)2, NHCOR5 and SR5 ; R2 is R6 or --CH=CH--R6 when R1 is COOR5, CONHR5, cyano or 5-tetrazolyl, or R2 is --CH=CH--R6 when R1 is R6 ; R3 is hydrogen, C1-6 alkyl, halogen, hydroxy or --OCH2 R6 ; and R4 is hydrogen, C1-6 alkyl or halogen; and salts thereof. The compounds have pharmaceutical properties and in particular are useful in the treatment of immediate hypersensitivity conditions such as asthma.