76793-03-8

Usage

Molecular structure

A complex structure with a bicyclic ring system, a morpholine group, and multiple methyl groups.

Molecular weight

Approximately 243.33 g/mol

Functional groups

Morpholine, alcohol, and methyl groups

Physical state

Likely a solid at room temperature, based on its molecular weight and complexity

Solubility

Unknown, but may be soluble in organic solvents like ethanol or methanol due to its nonpolar nature

Stability

Unknown, but may be sensitive to heat, light, or moisture due to the presence of an alcohol group

Reactivity

Unknown, but may react with strong acids, strong bases, or oxidizing agents

Applications

Potential use as a pharmaceutical intermediate or a building block for organic synthesis, but further research is needed

Research status

Not widely studied or used, with limited information available about its properties and potential applications

Safety

Unknown, but caution should be exercised when handling due to its complex structure and limited information

Environmental impact

Unknown, but potential environmental effects should be considered and further research conducted to assess its impact

Upstream product

• 76735-26-7 1,3,3-trimethyl-6-cis-morpholino-2-oxabicyclo<2.2.2>octan-5-one 
• 31316-32-2 4-((1R,4S)-1,3,3-Trimethyl-2-oxa-bicyclo[2.2.2]oct-5-en-6-yl)-morpholine 
• 76735-21-2 (1R,4S,5R,6S)-1,3,3-Trimethyl-6-morpholin-4-yl-2-oxa-bicyclo[2.2.2]octan-5-ol 

Downstream Products

• 76735-21-2 (1R,4S,5S,6S)-1,3,3-Trimethyl-6-morpholin-4-yl-2-oxa-bicyclo[2.2.2]octan-5-ol 

Relevant academic research and scientific papers

Carbonyl Transposition and Regio- and Stereo-specific Syntheses of New Alcohols, Amino-alcohols, and Ketones in the Monoterpenoid 1,3,3-Trimethyl-2-oxabicyclooctane

An efficient transposition of carbonyl group R1-CO-CH2-R2 -> R1-CH2-CO-R2 in the 1,3,3-trimethyl-2-oxabicyclooctane system was carried out via hydroboration-oxidation of 6-dialkylamino-1,3,3-trimethyl-2-oxabicyclooct-5-enes (3a-c), which gave regio- and stereo-specifically 6-cis-dialkylamino-1,3,3-trimethyl-2-oxabicyclooctan-5-trans-ols (4a-c) in high yield.Cope reaction on the N-oxide (5b) obtained from the amino-alcohol (4b) with hydrogen peroxide led to 1,3,3-trimethyl-2-oxabicyclooctan-5-one (6), the other possible isomer of the long-known 1,3,3-trimethyl-2-oxabicyclooctan-6-one (1b).The ketone (6) was also obtained from 1,3,3-trimethyl-2-oxabicyclooct-5-ene (2) via its trans-epoxide (11), lithium aluminium hydride reduction at 160-165 deg C of which gave stereo- and regio-specifically 1,3,3-trimethyl-2-oxabicyclooctan-5-trans-ol (9b).Chromic acid oxidation of (9b) and (4a-c) under various conditions gave the ketone (6) and the amino-ketones (7a-c), respectively.Lithium aluminium hydride reduction of (6) and (7a-c) afforded stereospecifically the cis-alcohol (9a) and 6-cis-dialkylamino-1,3,3-trimethyl-2-oxabicyclooctan-5-cis-ols (8a-c), respetively.Hydroboration-oxidation of the alkene (2) was not regiospecific, giving a 3:1 mixture of the trans-alcohols (9b) and (10b), respectively.