76807-64-2Relevant academic research and scientific papers
Pyridopyrimidines. 12. Synthesis of 8-deaza analogues of aminopterin and folic acid
Srinivasan, Ananthachari,Broom, Arthur D.
, p. 1777 - 1781 (2007/10/02)
A new, general approach to the synthesis of numerous 8-deazafolate and 8-deazaaminopterin analogues is described. The key intermediate, 6-(acetoxymethyl)-2,4-dichloropyrido[3,2-d]pyrimidine, was prepared by chlorination of the 2,4-dioxo derivative which,
